Propensity-Adjusted Comparative Analysis of Radial Versus Femoral Access for Neurointerventional Treatments

Joshua S. Catapano, Andrew F. Ducruet, Candice L. Nguyen, Neil Majmundar, D. Andrew Wilkinson, Tyler S. Cole, Jacob F. Baranoski, Daniel D. Cavalcanti, Vance L. Fredrickson, Visish M. Srinivasan, Caleb Rutledge, Michael T. Lawton, Felipe C. Albuquerque

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


BACKGROUND: Transradial artery (TRA) catheterization for neuroendovascular procedures is associated with a lower risk of complications than transfemoral artery (TFA) procedures. However, themajority of literature on TRA access pertains to diagnostic procedures rather than interventional treatments. OBJECTIVE: To compare TRA and TFA approaches for cerebrovascular interventions. METHODS: All patients with an endovascular intervention performed at a single center from October 1, 2018 to December 31, 2019 were retrospectively analyzed. Patients were grouped into 2 cohorts on the basis of whether TRA or TFA access was used. Outcomes included complications, fluoroscopy times, and total contrast administered. RESULTS: A total 579 interventional treatments were performed during the 15-mo study period. TFA procedures (n = 417) were associated with a significantly higher complication rate than TRA (n = 162) procedures (43 cases [10%] vs 5 cases [3%]; P = .008). After excluding patients who underwent thrombectomy and performing a propensity adjustment (including age, sex, pathology, procedure, sheath size, and catheter size), TRA catheterizationwas associated with decreased odds of a complication (odds ratio, 0.25; 95% CI 0.085-0.72; P = .01), but no significant difference in the amount of contrast administered (6.7-mL increase; 95% CI, -7.2 to 20.6; P = .34) or duration of fluoroscopy (2.1-min increase; 95% CI, -2.5 to 6.7; P = .37) compared with TFA catheterization. CONCLUSION: Neurointerventional procedures and treatments for a variety of pathologies can be performed successfully using the TRA approach, which is associated with a lower risk of complications and no difference in fluoroscopy duration compared with the TFA approach.

Original languageEnglish (US)
Pages (from-to)E505-E509
Issue number6
StatePublished - Jun 1 2021

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology


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