Prostaglandin levels in endometrial jet wash specimens in patients with dysmenorrhea before and after indomethacin therapy

David R. Halbert; Laurence M. Demers; John Fontana; D. E.Darnell Jones

doi:10.1016/S0090-6980(75)80052-9

Prostaglandin levels in endometrial jet wash specimens in patients with dysmenorrhea before and after indomethacin therapy

David R. Halbert, Laurence M. Demers, John Fontana, D. E.Darnell Jones

Department of Pathology and Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

A patient with functional primary dysmenorrhea of over two years duration was subjected to the endometrial jet wash technique during the period of active menstrual flow. Prostaglandin F analysis of the jet washings revealed significantly elevated levels during menstruation over normal control levels. Following indomethacin therapy, jet wash prostaglandin F levels were dramatically reduced and the patient became asymptomatic. A cause and effect relationship between prostaglandin F and dysmenorrhea is suggested by these studies.

Original language	English (US)
Pages (from-to)	1047-1056
Number of pages	10
Journal	Prostaglandins
Volume	10
Issue number	6
DOIs	https://doi.org/10.1016/S0090-6980(75)80052-9
State	Published - 1975

All Science Journal Classification (ASJC) codes

Biochemistry
Endocrinology

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10.1016/S0090-6980(75)80052-9

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title = "Prostaglandin levels in endometrial jet wash specimens in patients with dysmenorrhea before and after indomethacin therapy",

abstract = "A patient with functional primary dysmenorrhea of over two years duration was subjected to the endometrial jet wash technique during the period of active menstrual flow. Prostaglandin F analysis of the jet washings revealed significantly elevated levels during menstruation over normal control levels. Following indomethacin therapy, jet wash prostaglandin F levels were dramatically reduced and the patient became asymptomatic. A cause and effect relationship between prostaglandin F and dysmenorrhea is suggested by these studies.",

author = "Halbert, \{David R.\} and Demers, \{Laurence M.\} and John Fontana and Jones, \{D. E.Darnell\}",

year = "1975",

doi = "10.1016/S0090-6980(75)80052-9",

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volume = "10",

pages = "1047--1056",

journal = "Prostaglandins",

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T1 - Prostaglandin levels in endometrial jet wash specimens in patients with dysmenorrhea before and after indomethacin therapy

AU - Halbert, David R.

AU - Demers, Laurence M.

AU - Fontana, John

AU - Jones, D. E.Darnell

PY - 1975

Y1 - 1975

N2 - A patient with functional primary dysmenorrhea of over two years duration was subjected to the endometrial jet wash technique during the period of active menstrual flow. Prostaglandin F analysis of the jet washings revealed significantly elevated levels during menstruation over normal control levels. Following indomethacin therapy, jet wash prostaglandin F levels were dramatically reduced and the patient became asymptomatic. A cause and effect relationship between prostaglandin F and dysmenorrhea is suggested by these studies.

AB - A patient with functional primary dysmenorrhea of over two years duration was subjected to the endometrial jet wash technique during the period of active menstrual flow. Prostaglandin F analysis of the jet washings revealed significantly elevated levels during menstruation over normal control levels. Following indomethacin therapy, jet wash prostaglandin F levels were dramatically reduced and the patient became asymptomatic. A cause and effect relationship between prostaglandin F and dysmenorrhea is suggested by these studies.

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U2 - 10.1016/S0090-6980(75)80052-9

DO - 10.1016/S0090-6980(75)80052-9

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AN - SCOPUS:0016683396

SN - 0090-6980

VL - 10

SP - 1047

EP - 1056

JO - Prostaglandins

JF - Prostaglandins

IS - 6

ER -

Prostaglandin levels in endometrial jet wash specimens in patients with dysmenorrhea before and after indomethacin therapy

Abstract

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