Protease-inhibitory imbalance and inflammatory markers in cardiac surgery under artificial circulation

L. G. Knyaz’kova, V. V. Lomivorotov, S. A. Sergeev, T. A. Mogutnova, A. I. Subbotovskaya, V. S. Kozireva

Research output: Contribution to journalArticlepeer-review

Abstract

Elastase-inhibitory balance was studied during 36 cardiosurgical operations under artificial circulation, carried out in children aged 10,6±0,6 years with congenital heart diseases. It is estimated that imbalance in elastase-inhibitor system is mostly significant by the end of operation and in 2 hours after the operation. By the end of the first day increased level of protease inhibitors didn’t compensate high elastase level, and elastase-inhibitory coefficient remained higher that before the operation combined with increased inflammatory markers.. It is drawn a conclusion that imbalance in protease-inhibitory system after the operation is a risk factor for complications and indicates necessity of its correction.

Original languageEnglish (US)
Pages (from-to)84-87
Number of pages4
JournalKardiologiya i Serdechno-Sosudistaya Khirurgiya
Volume5
Issue number1
StatePublished - 2012

All Science Journal Classification (ASJC) codes

  • Surgery
  • Cardiology and Cardiovascular Medicine

Fingerprint

Dive into the research topics of 'Protease-inhibitory imbalance and inflammatory markers in cardiac surgery under artificial circulation'. Together they form a unique fingerprint.

Cite this