Protein biomarkers of alcohol abuse

Mariana P. Torrente; Willard M. Freeman; Kent E. Vrana

doi:10.1586/epr.12.38

Protein biomarkers of alcohol abuse

Mariana P. Torrente, Willard M. Freeman, Kent E. Vrana

Research output: Contribution to journal › Review article › peer-review

25 Scopus citations

Abstract

Alcohol abuse can lead to a number of health and social issues. Our current inability to accurately assess long-term drinking behaviors is an important obstacle to its diagnosis and treatment. Biomarkers for chronic alcohol consumption have made a number of important advances but have yet to become highly accurate and as accepted as objective tests for other diseases. Thus, there is a crucial need for the development of more sensitive and specific markers of alcohol abuse. Recent advancements in proteomic technologies have greatly increased the potential for alcohol abuse biomarker discovery. Here, the authors review established and novel protein biomarkers for long-term alcohol consumption and the proteomic technologies that have been used in their study.

Original language	English (US)
Pages (from-to)	425-436
Number of pages	12
Journal	Expert Review of Proteomics
Volume	9
Issue number	4
DOIs	https://doi.org/10.1586/epr.12.38
State	Published - Aug 2012

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology

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10.1586/epr.12.38

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title = "Protein biomarkers of alcohol abuse",

abstract = "Alcohol abuse can lead to a number of health and social issues. Our current inability to accurately assess long-term drinking behaviors is an important obstacle to its diagnosis and treatment. Biomarkers for chronic alcohol consumption have made a number of important advances but have yet to become highly accurate and as accepted as objective tests for other diseases. Thus, there is a crucial need for the development of more sensitive and specific markers of alcohol abuse. Recent advancements in proteomic technologies have greatly increased the potential for alcohol abuse biomarker discovery. Here, the authors review established and novel protein biomarkers for long-term alcohol consumption and the proteomic technologies that have been used in their study.",

author = "Torrente, {Mariana P.} and Freeman, {Willard M.} and Vrana, {Kent E.}",

note = "Funding Information: MP Torrente gratefully acknowledges support from the NIH in the form of a F32 NRSA postdoctoral fellowship (5F32MH094071) as well as a Neuroscience Career Development Fellowship from the Society for Neuroscience. This work was also supported by grants from the NIH to KE Vrana and WM Freeman (AA016613-03). WM Freeman and KE Vrana report a patent pending on diagnostics of alcohol intake. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.",

year = "2012",

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doi = "10.1586/epr.12.38",

language = "English (US)",

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AU - Torrente, Mariana P.

AU - Freeman, Willard M.

AU - Vrana, Kent E.

N1 - Funding Information: MP Torrente gratefully acknowledges support from the NIH in the form of a F32 NRSA postdoctoral fellowship (5F32MH094071) as well as a Neuroscience Career Development Fellowship from the Society for Neuroscience. This work was also supported by grants from the NIH to KE Vrana and WM Freeman (AA016613-03). WM Freeman and KE Vrana report a patent pending on diagnostics of alcohol intake. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

PY - 2012/8

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N2 - Alcohol abuse can lead to a number of health and social issues. Our current inability to accurately assess long-term drinking behaviors is an important obstacle to its diagnosis and treatment. Biomarkers for chronic alcohol consumption have made a number of important advances but have yet to become highly accurate and as accepted as objective tests for other diseases. Thus, there is a crucial need for the development of more sensitive and specific markers of alcohol abuse. Recent advancements in proteomic technologies have greatly increased the potential for alcohol abuse biomarker discovery. Here, the authors review established and novel protein biomarkers for long-term alcohol consumption and the proteomic technologies that have been used in their study.

AB - Alcohol abuse can lead to a number of health and social issues. Our current inability to accurately assess long-term drinking behaviors is an important obstacle to its diagnosis and treatment. Biomarkers for chronic alcohol consumption have made a number of important advances but have yet to become highly accurate and as accepted as objective tests for other diseases. Thus, there is a crucial need for the development of more sensitive and specific markers of alcohol abuse. Recent advancements in proteomic technologies have greatly increased the potential for alcohol abuse biomarker discovery. Here, the authors review established and novel protein biomarkers for long-term alcohol consumption and the proteomic technologies that have been used in their study.

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Protein biomarkers of alcohol abuse

Abstract

All Science Journal Classification (ASJC) codes

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