Protein engineering boosts monooxygenase activity

Research output: Contribution to specialist publicationArticle


A team of researchers at the University of Connecticut identified a number of novel monooxygenase enzymes that act on some aromatic compounds. The enzyme, a toluene 4-monoxygenase that oxidizes nitrobenzene to 4-nitrocatechol was identified from Pseudomonas mendocina KR1. Nitrocatechol-producing mutants were discovered by screening 550 colonies from a random mutagenesis library on agar plates containing nitrobenzene.

Original languageEnglish (US)
Number of pages2
Specialist publicationIndustrial Bioprocessing
StatePublished - Oct 1 2004

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biochemistry
  • Chemical Engineering(all)
  • Organic Chemistry


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