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Protein function analysis: Rapid, cell-based SiRNA-mediated ablation of endogenous expression with simultaneous ectopic replacement
Brett C. DiNatale,
Gary H. Perdew
Veterinary and Biomedical Sciences
Penn State Cancer Institute
Cancer Institute, Mechanisms of Carcinogenesis
Research output
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Contribution to journal
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Article
›
peer-review
4
Scopus citations
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Dive into the research topics of 'Protein function analysis: Rapid, cell-based SiRNA-mediated ablation of endogenous expression with simultaneous ectopic replacement'. Together they form a unique fingerprint.
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Keyphrases
Cell-based
100%
Small Interfering RNA (siRNA)
100%
Ablation
100%
Endogenous Expression
100%
Oligonucleotides
50%
Endogenous Protein
50%
Codon Optimization
50%
Complementary DNA (cDNA)
25%
Protein Level
25%
Breast Cancer Cell Lines
25%
MCF-7
25%
Electroporation
25%
Coding Sequence
25%
Specificity Protein 1
25%
Cytochrome P450 1A1 (CYP1A1)
25%
Vector Encoding
25%
Native Ecosystems
25%
Simultaneous Expression
25%
Designed Proteins
25%
Transfection Efficiency
25%
B(a)P
25%
Biochemistry, Genetics and Molecular Biology
Protein Function
100%
Small Interfering RNA
100%
Oligonucleotide
66%
Codon
66%
Transcription
33%
Cancer Cell
33%
Transfection
33%
Electroporation
33%