Proton pump inhibitors and the risk of acquiring a penicillin allergy label

Sarah Al-Obaydi; Catherine A. Popadiuk; Taha Al-Shaikhly

doi:10.1111/imj.16197

Proton pump inhibitors and the risk of acquiring a penicillin allergy label

Sarah Al-Obaydi, Catherine A. Popadiuk, Taha Al-Shaikhly

Research output: Contribution to journal › Article › peer-review

Abstract

The negative consequences of having a penicillin allergy label are well established. Penicillin allergy de-labelling improves healthcare outcomes; however, less attention is paid to modifying risk factors leading to penicillin allergy development. In this propensity score-matched retrospective cohort study, we used a de-identified population-based database (TriNetX Research Network) and examined the 30-day risk of acquiring a penicillin allergy label in patients using proton pump inhibitors (PPIs). We demonstrated a higher risk of acquiring a penicillin allergy label among PPI users compared to controls.

Original language	English (US)
Pages (from-to)	1481-1484
Number of pages	4
Journal	Internal Medicine Journal
Volume	53
Issue number	8
DOIs	https://doi.org/10.1111/imj.16197
State	Published - Aug 2023

All Science Journal Classification (ASJC) codes

Internal Medicine

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10.1111/imj.16197

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title = "Proton pump inhibitors and the risk of acquiring a penicillin allergy label",

abstract = "The negative consequences of having a penicillin allergy label are well established. Penicillin allergy de-labelling improves healthcare outcomes; however, less attention is paid to modifying risk factors leading to penicillin allergy development. In this propensity score-matched retrospective cohort study, we used a de-identified population-based database (TriNetX Research Network) and examined the 30-day risk of acquiring a penicillin allergy label in patients using proton pump inhibitors (PPIs). We demonstrated a higher risk of acquiring a penicillin allergy label among PPI users compared to controls.",

author = "Sarah Al-Obaydi and Popadiuk, {Catherine A.} and Taha Al-Shaikhly",

note = "Funding Information: The project described was supported by the National Center for Advancing Translational Sciences, National Institutes of Health, through Grant UL1 TR002014. Publisher Copyright: {\textcopyright} 2023 The Authors. Internal Medicine Journal published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Physicians.",

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AB - The negative consequences of having a penicillin allergy label are well established. Penicillin allergy de-labelling improves healthcare outcomes; however, less attention is paid to modifying risk factors leading to penicillin allergy development. In this propensity score-matched retrospective cohort study, we used a de-identified population-based database (TriNetX Research Network) and examined the 30-day risk of acquiring a penicillin allergy label in patients using proton pump inhibitors (PPIs). We demonstrated a higher risk of acquiring a penicillin allergy label among PPI users compared to controls.

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Proton pump inhibitors and the risk of acquiring a penicillin allergy label

Abstract

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