TY - JOUR
T1 - Pseudoenhancement of renal cysts
T2 - Influence of lesion size, lesion location, slice thickness, and number of MDCT detectors
AU - Tappouni, Rafel
AU - Kissane, Jennifer
AU - Sarwani, Nabeel
AU - Lehman, Erik B.
N1 - Copyright:
Copyright 2012 Elsevier B.V., All rights reserved.
PY - 2012/1
Y1 - 2012/1
N2 - OBJECTIVE. The purpose of this study was to determine the effect of renal cyst size and location on pseudoenhancement in human subjects. MATERIALS AND METHODS. Simple renal cysts obtained with 16-, 40-, and 64-MDCT scanners were analyzed for the presence of pseudoenhancement. Cyst size, location, and attenuation in the unenhanced and nephrographic phases were recorded. Pseudoenhancement was defined as an attenuation increase of 10 HU or more on nephrographic phase compared with unenhanced images. RESULTS. The pseudoenhancement rate was 22% (51/233). There was a statistically significant increase in the pseudoenhancement rate of lesions smaller than 10 mm (38/233) compared with those 10 mm and larger (13/233) (odds ratio, 6.4; p < 0.0001). Twelve of 62 cysts measuring 10-14 mm exhibited pseudoenhancement. There was a statistically significant increase in the pseudoenhancement rate of central (39/53) compared with peripheral (12/51) cysts (odds ratio, 2.7; p < 0.0001). The pseudoenhancement rates for the 16-, 40-, and 64-MDCT scanners were 20%, 19%, and 26% with no statistically significant difference between them. CONCLUSION. Pseudoenhancement of renal cysts significantly correlates with size smaller than 1 cm and central location. Although pseudoenhancement increases with larger numbers of detectors, the correlation was not statistically significant. Cysts in the 1- to 1.5-cm range have a 19% likelihood of pseudoenhancement.
AB - OBJECTIVE. The purpose of this study was to determine the effect of renal cyst size and location on pseudoenhancement in human subjects. MATERIALS AND METHODS. Simple renal cysts obtained with 16-, 40-, and 64-MDCT scanners were analyzed for the presence of pseudoenhancement. Cyst size, location, and attenuation in the unenhanced and nephrographic phases were recorded. Pseudoenhancement was defined as an attenuation increase of 10 HU or more on nephrographic phase compared with unenhanced images. RESULTS. The pseudoenhancement rate was 22% (51/233). There was a statistically significant increase in the pseudoenhancement rate of lesions smaller than 10 mm (38/233) compared with those 10 mm and larger (13/233) (odds ratio, 6.4; p < 0.0001). Twelve of 62 cysts measuring 10-14 mm exhibited pseudoenhancement. There was a statistically significant increase in the pseudoenhancement rate of central (39/53) compared with peripheral (12/51) cysts (odds ratio, 2.7; p < 0.0001). The pseudoenhancement rates for the 16-, 40-, and 64-MDCT scanners were 20%, 19%, and 26% with no statistically significant difference between them. CONCLUSION. Pseudoenhancement of renal cysts significantly correlates with size smaller than 1 cm and central location. Although pseudoenhancement increases with larger numbers of detectors, the correlation was not statistically significant. Cysts in the 1- to 1.5-cm range have a 19% likelihood of pseudoenhancement.
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U2 - 10.2214/AJR.10.6057
DO - 10.2214/AJR.10.6057
M3 - Article
C2 - 22194488
AN - SCOPUS:84455209479
SN - 0361-803X
VL - 198
SP - 133
EP - 137
JO - American Journal of Roentgenology
JF - American Journal of Roentgenology
IS - 1
ER -