Psychoneuroimmunology and Cancer: Mechanisms Explaining Incidence, Progression, and Quality-of-Life Difficulties

Lauren E. Chu, Angie S. Leroy, Christopher P. Fagundes, Kyle W. Murdock

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Psychological correlates of cancer incidence, progression, and quality-of-life difficulties have been well-documented in the literature; however, recent developments in psychoneuroimmunology (PNI) may provide further confirmation for the relationship between psychological factors and cancer. In this chapter, we review the current literature on how psychosocial factors (e.g., depression, marital support) and physiological processes (e.g., glucocorticoids) impact cancer incidence and progression. We then explore cutting-edge research on the biological mechanisms (e.g., bioenergetic health) that may explain quality-of-life difficulties among cancer survivors. Finally, we review studies that use biomarkers (e.g., pro-inflammatory cytokines) to evaluate the effectiveness of psychosocial intervention strategies.

Original languageEnglish (US)
Title of host publicationPsychological Aspects of Cancer
Subtitle of host publicationa Guide to Emotional and Psychological Consequences of Cancer, their Causes, and their Management, Second Edition
PublisherSpringer International Publishing
Pages147-157
Number of pages11
ISBN (Electronic)9783030857028
ISBN (Print)9783030857011
DOIs
StatePublished - Jan 1 2022

All Science Journal Classification (ASJC) codes

  • General Medicine
  • General Psychology

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