Pulmonary Host Defenses

Herbert Y. Reynolds

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Well functioning host defenses in the respiratory tract effectively remove microbes and other debris that reach the conducting airways and alveoli, and this usually prevents infections. People with acute and chronic illnesses can experience failure of any number of these defense mechanisms that allow pneumonia (and bacteremia) to occur, often with considerable morbidity and mortality. People with alcohol‐related illnesses are a susceptible group for infections, and many strategies are needed to help them such as moderating alcohol abuse and dependence, providing timely immunizations to create antibody against encapsulated bacteria, anticipating microbial colonization of mucosal areas that can promote infection, giving excellent supporting medical care in crisis situations, and prescribing appropriate antibiotics. New approaches to boosting inflammatory reactions to control lung infections better with cytokines and new immunomodulator therapies must be investigated now.

Original languageEnglish (US)
Pages (from-to)6-10
Number of pages5
JournalAlcoholism: Clinical and Experimental Research
Issue number1
StatePublished - Feb 1995

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Toxicology
  • Psychiatry and Mental health


Dive into the research topics of 'Pulmonary Host Defenses'. Together they form a unique fingerprint.

Cite this