Pulmonary resection following lung transplantation

John Conte, J. B. Orens, J. R. Sonett, M. C. Borja, J. S. McLaughlin

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: Pulmonary resections (PR) are unusual post lung transplantation (LT) and the literature consists primarily of isolated case reports. We reviewed our experience with PR post LT and report our experience. Methods: Fifty-four LT were performed over a 30 month period. There were 38 single LT, 15 bilateral LT and 1 heartlung. Median follow-up was 446 days (30-999). Five patients (9%) underwent PR following LT. Three pts underwent unilateral lung volume reduction surgery(LVRS) for native lung hyperinflation a median of 206 days post single LT for COPD. Two thoracoscopic and one open procedure was performed for clinical deterioration quantified by spirometry and confirmed by radiographs. One pt died of respiratory failure following open LVRS. Improvements were seen in FEV1, FVC, TLC, and RV Two patients underwent lobectomy for infectious causes. One patient underwent native lobectomy for an aspergilloma 270 days post single LT for IPF and one pt underwent transplant lobectomy for bronchiectasis 52 days following bilateral LT. No morbidity was seen in any survivors and all were discharged within 12 days of surgery. Conclusions: We conclude that PR can be safely performed post LT for infectious and non-infectious causes with reasonable morbidity and mortality.

Original languageEnglish (US)
JournalCHEST
Volume114
Issue number4 SUPPL.
StatePublished - Oct 1 1998

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

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