Abstract
The amount of S adenosyl L methionine decarboxylase present in rat liver was enhanced 17 fold by administration of methylglyoxal bis(guanylhydrazone), a specific inhibitor of the enzyme. The enzyme was purified 1400 fold in 50% yield from such liver extracts by chromatography on columns of the inhibitor bound to Sepharose. The purified enzyme had no spermidine synthetase activity.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 581-583 |
| Number of pages | 3 |
| Journal | Biochemical Journal |
| Volume | 141 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1974 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Molecular Biology
- Cell Biology