Qualitative evaluation of thermal desorption-programmable temperature vaporization-comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry for the analysis of selected halogenated contaminants

Jean François Focant; Andreas Sjödin; Donald G. Patterson

doi:10.1016/j.chroma.2003.07.007

Qualitative evaluation of thermal desorption-programmable temperature vaporization-comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry for the analysis of selected halogenated contaminants

Jean François Focant
, Andreas Sjödin
, Donald G. Patterson

Forensic Science Program

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

The separation of 38 toxic and predominant polychlorinated biphenyl (PCB) congeners, 11 persistent halogenated pesticides, 1 brominated biphenyl (BB), and 8 polybrominated diphenyl ethers (PBDEs) has been optimized using comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC×GC-TOFMS). A thermal desorption-programmable temperature vaporization (TD-PTV) step was used for the injection. Different column sets were investigated, and a 100% dimethylpolysiloxane (15m×0.25mm i.d.×0.25μm film thickness) narrowbore capillary column coupled to a high temperature (8% phenyl)-polycarborane-siloxane (2m×0.10mm i.d.×0.10μm film thickness) microbore column set was selected. Of the 58 compounds investigated, only one pair of PCBs was not resolved. All other analytes were either baseline separated into the chromatographic plane or were virtually separated using the deconvolution capability of the TOFMS.

Original language	English (US)
Pages (from-to)	143-156
Number of pages	14
Journal	Journal of Chromatography A
Volume	1019
Issue number	1-2
DOIs	https://doi.org/10.1016/j.chroma.2003.07.007
State	Published - Nov 26 2003

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Biochemistry
Organic Chemistry

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10.1016/j.chroma.2003.07.007

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@article{683642d3ed6b48a0816ba9d00e7210fb,

title = "Qualitative evaluation of thermal desorption-programmable temperature vaporization-comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry for the analysis of selected halogenated contaminants",

abstract = "The separation of 38 toxic and predominant polychlorinated biphenyl (PCB) congeners, 11 persistent halogenated pesticides, 1 brominated biphenyl (BB), and 8 polybrominated diphenyl ethers (PBDEs) has been optimized using comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC×GC-TOFMS). A thermal desorption-programmable temperature vaporization (TD-PTV) step was used for the injection. Different column sets were investigated, and a 100\% dimethylpolysiloxane (15m×0.25mm i.d.×0.25μm film thickness) narrowbore capillary column coupled to a high temperature (8\% phenyl)-polycarborane-siloxane (2m×0.10mm i.d.×0.10μm film thickness) microbore column set was selected. Of the 58 compounds investigated, only one pair of PCBs was not resolved. All other analytes were either baseline separated into the chromatographic plane or were virtually separated using the deconvolution capability of the TOFMS.",

author = "Focant, \{Jean Fran{\c c}ois\} and Andreas Sj{\"o}din and Patterson, \{Donald G.\}",

note = "Funding Information: J.-F. Focant is financially supported by the Oak Ridge Institute for Science and Education (ORISE), a Department of Energy (DOE) facility managed by Oak Ridge Associated Universities (ORAU). ",

year = "2003",

month = nov,

day = "26",

doi = "10.1016/j.chroma.2003.07.007",

language = "English (US)",

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Focant, JF, Sjödin, A & Patterson, DG 2003, 'Qualitative evaluation of thermal desorption-programmable temperature vaporization-comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry for the analysis of selected halogenated contaminants', Journal of Chromatography A, vol. 1019, no. 1-2, pp. 143-156. https://doi.org/10.1016/j.chroma.2003.07.007

Qualitative evaluation of thermal desorption-programmable temperature vaporization-comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry for the analysis of selected halogenated contaminants. / Focant, Jean François; Sjödin, Andreas; Patterson, Donald G.
In: Journal of Chromatography A, Vol. 1019, No. 1-2, 26.11.2003, p. 143-156.

Research output: Contribution to journal › Article › peer-review

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AU - Focant, Jean François

AU - Sjödin, Andreas

AU - Patterson, Donald G.

N1 - Funding Information: J.-F. Focant is financially supported by the Oak Ridge Institute for Science and Education (ORISE), a Department of Energy (DOE) facility managed by Oak Ridge Associated Universities (ORAU).

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Y1 - 2003/11/26

N2 - The separation of 38 toxic and predominant polychlorinated biphenyl (PCB) congeners, 11 persistent halogenated pesticides, 1 brominated biphenyl (BB), and 8 polybrominated diphenyl ethers (PBDEs) has been optimized using comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC×GC-TOFMS). A thermal desorption-programmable temperature vaporization (TD-PTV) step was used for the injection. Different column sets were investigated, and a 100% dimethylpolysiloxane (15m×0.25mm i.d.×0.25μm film thickness) narrowbore capillary column coupled to a high temperature (8% phenyl)-polycarborane-siloxane (2m×0.10mm i.d.×0.10μm film thickness) microbore column set was selected. Of the 58 compounds investigated, only one pair of PCBs was not resolved. All other analytes were either baseline separated into the chromatographic plane or were virtually separated using the deconvolution capability of the TOFMS.

AB - The separation of 38 toxic and predominant polychlorinated biphenyl (PCB) congeners, 11 persistent halogenated pesticides, 1 brominated biphenyl (BB), and 8 polybrominated diphenyl ethers (PBDEs) has been optimized using comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC×GC-TOFMS). A thermal desorption-programmable temperature vaporization (TD-PTV) step was used for the injection. Different column sets were investigated, and a 100% dimethylpolysiloxane (15m×0.25mm i.d.×0.25μm film thickness) narrowbore capillary column coupled to a high temperature (8% phenyl)-polycarborane-siloxane (2m×0.10mm i.d.×0.10μm film thickness) microbore column set was selected. Of the 58 compounds investigated, only one pair of PCBs was not resolved. All other analytes were either baseline separated into the chromatographic plane or were virtually separated using the deconvolution capability of the TOFMS.

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Qualitative evaluation of thermal desorption-programmable temperature vaporization-comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry for the analysis of selected halogenated contaminants

Abstract

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