Quantifying analytes in paper-based microfluidic devices without using external electronic readers

Gregory G. Lewis, Matthew J. Ditucci, Scott T. Phillips

Research output: Contribution to journalArticlepeer-review

145 Scopus citations

Abstract

A matter of time: Two quantitative assays are presented that require only measurements of time and the ability to see and/or count to quantify the presence of a specific analyte. The strategies rely on specific changes in wetting properties of paper when a hydrophobic detection reagent (compound 1) reacts with a desired analyte to produce hydrophilic products. This change in wetting properties enables selective and quantitative detection of the analyte.

Original languageEnglish (US)
Pages (from-to)12707-12710
Number of pages4
JournalAngewandte Chemie - International Edition
Volume51
Issue number51
DOIs
StatePublished - Dec 14 2012

All Science Journal Classification (ASJC) codes

  • Catalysis
  • General Chemistry

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