Quantifying EGFR alterations in the lung cancer genome with nanofluidic digital PCR arrays

Keyphrases

• Droplet Digital PCR (ddPCR) 100%
• Lung Cancer 100%
• Cancer Genome 100%
• Nanofluidics 100%
• PCR Array 100%
• Lung Tumor 75%
• Clinical Response 50%
• Clinically Significant 50%
• Oncogene 50%
• Gene Copy number 50%
• EGFR-targeting 50%
• EGFR Gene 50%
• Scorpion 50%
• Targeted Inhibitors 50%
• TaqMan Assay 25%
• Copy number 25%
• Viral 25%
• Tumor Progression 25%
• Genomic DNA (gDNA) 25%
• Formalin-fixed Paraffin-embedded Tissue 25%
• Genetic Modification 25%
• Molecular Changes 25%
• Gene Amplification 25%
• Single-copy Gene 25%
• Leukemia 25%
• Locally Advanced Non-small Cell Lung Cancer (LA-NSCLC) 25%
• Fluorescein Diacetate 25%
• Rhodamine B (Rh B) 25%
• Epidermal Growth Factor Receptor 25%
• Tumor Stage 25%
• Cancer Tumor 25%
• Erlotinib 25%
• Ribonuclease P 25%
• In-frame Deletion 25%
• Gefitinib 25%
• Exon 19 25%
• Mutation Testing 25%
• Qiagen 25%
• Molecular Heterogeneity 25%
• Single Molecule Level 25%
• EGFR mutation 25%
• Intratumor 25%
• EGFR T790M 25%

Biochemistry, Genetics and Molecular Biology

• Epidermal Growth Factor Receptor 100%
• Allele 15%
• Kinase 15%
• Phosphotransferase 15%
• Exon 15%
• Oncogene 15%
• Genomics 15%
• Tumor Progression 7%
• Gene Amplification 7%
• Gene Dosage 7%
• Carboxyfluorescein 7%
• Rhodamine 7%
• TaqMan 7%
• RNase P 7%
• Gefitinib 7%
• Erlotinib 7%
• Cancer Staging 7%
• Aves 7%