Quantitative methods and bayesian models for flow cytometry analysis in HIV/AIDS research

Lin Lin, Cliburn Chan

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Flow cytometry is a multiparameter single-cell assay ubiquitous in HIV/AIDS clinical and research settings for evaluating the immune response to the virus, therapy, and vaccination. In clinical practice, flow cytometry is used to monitor the CD4 and CD8 T cell counts of HIV-infected subjects. In research settings, flow cytometry is used to evaluate innate and antigen-specific responses to the HIV virus, so as to better understand pathogenesis, the mechanisms responsible for long-term nonprogression, and to develop effective immune-based interventions. In vaccine development, there is significant interest in the potential of flow-based biomarkers that can serve as surrogate measures of efficacy.

Original languageEnglish (US)
Title of host publicationQuantitative Methods for HIV/AIDS Research
PublisherCRC Press
Number of pages22
ISBN (Electronic)9781498734257
ISBN (Print)9781498734233
StatePublished - Jan 1 2017

All Science Journal Classification (ASJC) codes

  • General Mathematics
  • General Medicine


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