Abstract
Autoinducer 2 (AI-2) quorum sensing was shown before to regulate the virulence of Vibrio harveyi towards the brine shrimp Artemia franciscana. In this study, several different pathogenic V. harveyi, Vibrio campbellii, and Vibrio parahaemolyticus isolates were shown to produce AI-2. Furthermore, disruption of AI-2 quorum sensing by a natural and a synthetic brominated furanone protected gnotobiotic Artemia from the pathogenic isolates in in vivo challenge tests.
Original language | English (US) |
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Pages (from-to) | 6419-6423 |
Number of pages | 5 |
Journal | Applied and environmental microbiology |
Volume | 72 |
Issue number | 9 |
DOIs | |
State | Published - Sep 2006 |
All Science Journal Classification (ASJC) codes
- Biotechnology
- Food Science
- Applied Microbiology and Biotechnology
- Ecology