Treatment of patients with unresectable stage Ilia and IIIB non-small cell lung cancer with conventional radiation therapy has resulted in poor local control, a high rate of systemic failure, and 5-year survival of less than 10%. Recent modification in radiation treatment planning, dose delivery, and fractionization has demonstrated significantly improved median and 2- year survival, comparable in some trials to that achieved with induction chemotherapy followed by radiation. Current trials focus on combining systemic therapy with dose-intense radiation therapy to improve with local and systemic control.
|Number of pages
|Seminars in Oncology
|Published - 1997
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