Radiogenomics of Gliomas

Chaitra Badve; Sangam Kanekar

doi:10.1016/j.rcl.2021.02.002

Radiogenomics of Gliomas

Chaitra Badve, Sangam Kanekar

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

The 2016 World Health Organization brain tumor classification is based on genomic and molecular profile of tumor tissue. These characteristics have improved understanding of the brain tumor and played an important role in treatment planning and prognostication. There is an ongoing effort to develop noninvasive imaging techniques that provide insight into tissue characteristics at the cellular and molecular levels. This article focuses on the molecular characteristics of gliomas, transcriptomic subtypes, and radiogenomic studies using semantic and radiomic features. The limitations and future directions of radiogenomics as a standalone diagnostic tool also are discussed.

Original language	English (US)
Pages (from-to)	441-455
Number of pages	15
Journal	Radiologic Clinics of North America
Volume	59
Issue number	3
DOIs	https://doi.org/10.1016/j.rcl.2021.02.002
State	Published - May 1 2021

All Science Journal Classification (ASJC) codes

Radiology Nuclear Medicine and imaging

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10.1016/j.rcl.2021.02.002

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title = "Radiogenomics of Gliomas",

abstract = "The 2016 World Health Organization brain tumor classification is based on genomic and molecular profile of tumor tissue. These characteristics have improved understanding of the brain tumor and played an important role in treatment planning and prognostication. There is an ongoing effort to develop noninvasive imaging techniques that provide insight into tissue characteristics at the cellular and molecular levels. This article focuses on the molecular characteristics of gliomas, transcriptomic subtypes, and radiogenomic studies using semantic and radiomic features. The limitations and future directions of radiogenomics as a standalone diagnostic tool also are discussed.",

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year = "2021",

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doi = "10.1016/j.rcl.2021.02.002",

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AU - Kanekar, Sangam

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AB - The 2016 World Health Organization brain tumor classification is based on genomic and molecular profile of tumor tissue. These characteristics have improved understanding of the brain tumor and played an important role in treatment planning and prognostication. There is an ongoing effort to develop noninvasive imaging techniques that provide insight into tissue characteristics at the cellular and molecular levels. This article focuses on the molecular characteristics of gliomas, transcriptomic subtypes, and radiogenomic studies using semantic and radiomic features. The limitations and future directions of radiogenomics as a standalone diagnostic tool also are discussed.

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M3 - Review article

C2 - 33926688

AN - SCOPUS:85105204197

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EP - 455

JO - Radiologic Clinics of North America

JF - Radiologic Clinics of North America

IS - 3

ER -

Radiogenomics of Gliomas

Abstract

All Science Journal Classification (ASJC) codes

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