Rapid detection of campylobacter antigen by enzyme immunoassay leads to increased positivity rates

Carmen L. Giltner; Sandra Saeki; April M. Bobenchik; Romney M. Humphries

doi:10.1128/JCM.02565-12

Rapid detection of campylobacter antigen by enzyme immunoassay leads to increased positivity rates

Carmen L. Giltner, Sandra Saeki, April M. Bobenchik, Romney M. Humphries

Department of Pathology and Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Campylobacter antigen detection by enzyme immunoassay (EIA) provides rapid results compared to traditional culture. However, concern exists regarding specificity. Verification studies of an EIA compared to culture revealed a positive predictive value (PPV) of 91%, whereas PPV fell to 42% during routine diagnostic testing. We suggest all positive EIA results be confirmed via culture.

Original language	English (US)
Pages (from-to)	618-620
Number of pages	3
Journal	Journal of clinical microbiology
Volume	51
Issue number	2
DOIs	https://doi.org/10.1128/JCM.02565-12
State	Published - Feb 2013

All Science Journal Classification (ASJC) codes

Microbiology (medical)

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10.1128/JCM.02565-12

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title = "Rapid detection of campylobacter antigen by enzyme immunoassay leads to increased positivity rates",

abstract = "Campylobacter antigen detection by enzyme immunoassay (EIA) provides rapid results compared to traditional culture. However, concern exists regarding specificity. Verification studies of an EIA compared to culture revealed a positive predictive value (PPV) of 91%, whereas PPV fell to 42% during routine diagnostic testing. We suggest all positive EIA results be confirmed via culture.",

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AU - Humphries, Romney M.

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AB - Campylobacter antigen detection by enzyme immunoassay (EIA) provides rapid results compared to traditional culture. However, concern exists regarding specificity. Verification studies of an EIA compared to culture revealed a positive predictive value (PPV) of 91%, whereas PPV fell to 42% during routine diagnostic testing. We suggest all positive EIA results be confirmed via culture.

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Rapid detection of campylobacter antigen by enzyme immunoassay leads to increased positivity rates

Abstract

All Science Journal Classification (ASJC) codes

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