40 Scopus citations


Molecular genetics has proved quite successful in identifying the components of RAS-mediated signal transduction in the yeast Saccharomyces cerevisiae and in defining the nature of their interactions. Recently, the emphasis has shifted to a biochemical approach as the processes of guanine nucleotide exchange, GTPase stimulation activity and post-translational modification of Ras proteins have all been reproduced in vitro.

Original languageEnglish (US)
Pages (from-to)370-377
Number of pages8
JournalCurrent Opinion in Genetics and Development
Issue number3
StatePublished - Oct 1991

All Science Journal Classification (ASJC) codes

  • Genetics
  • Developmental Biology


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