TY - JOUR
T1 - Ratio of intra-operative fluid to anesthesia time and its impact on short term perioperative outcomes following gastrectomy for cancer
T2 - A retrospective cohort study
AU - Enomoto, Laura M.
AU - Blackham, Aaron
AU - Woo, Yanghee
AU - Yamamoto, Maki
AU - Pimiento, Jose
AU - Gusani, Niraj J.
AU - Wong, Joyce
N1 - Publisher Copyright:
© 2016 IJS Publishing Group Ltd
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Background This study evaluates the short-term impact of fluid administration during gastrectomy for cancer. Methods A multi-institutional database of patients undergoing gastrectomy for cancer from three tertiary centers was reviewed. Logistic and linear regression analyses were performed. Results 205 patients were included. The majority of patients (n = 116, 57%) underwent proximal or total gastrectomy. Median anesthesia time was 280 min (range 95–691 min). Median intraoperative crystalloid administration was 2901 ml (range 500–10,700 ml). Median colloid administration was 0 (range 0–3835 ml), although only 66 patients (32%) received colloid. On multivariate analysis, patients who received <10.0 ml total fluid per minute of anesthesia had a significantly higher risk of complications (OR 4.12, p = 0.010). Crystalloid and total fluid administration ratios did not significantly affect LOS or discharge disposition. Conclusions Restricting intra-operative fluid resuscitation to <10 ml total fluid per minute anesthesia is associated with an increased risk of complications in patients undergoing gastrectomy for cancer.
AB - Background This study evaluates the short-term impact of fluid administration during gastrectomy for cancer. Methods A multi-institutional database of patients undergoing gastrectomy for cancer from three tertiary centers was reviewed. Logistic and linear regression analyses were performed. Results 205 patients were included. The majority of patients (n = 116, 57%) underwent proximal or total gastrectomy. Median anesthesia time was 280 min (range 95–691 min). Median intraoperative crystalloid administration was 2901 ml (range 500–10,700 ml). Median colloid administration was 0 (range 0–3835 ml), although only 66 patients (32%) received colloid. On multivariate analysis, patients who received <10.0 ml total fluid per minute of anesthesia had a significantly higher risk of complications (OR 4.12, p = 0.010). Crystalloid and total fluid administration ratios did not significantly affect LOS or discharge disposition. Conclusions Restricting intra-operative fluid resuscitation to <10 ml total fluid per minute anesthesia is associated with an increased risk of complications in patients undergoing gastrectomy for cancer.
UR - http://www.scopus.com/inward/record.url?scp=84979258479&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84979258479&partnerID=8YFLogxK
U2 - 10.1016/j.ijsu.2016.07.006
DO - 10.1016/j.ijsu.2016.07.006
M3 - Article
C2 - 27394407
AN - SCOPUS:84979258479
SN - 1743-9191
VL - 33
SP - 13
EP - 17
JO - International Journal of Surgery
JF - International Journal of Surgery
ER -