Rational Design and Synthesis of Isatin-Chalcone Hybrids Integrated with 1H-1,2,3-Triazole: Anti-Proliferative Profiling and Molecular Docking Insights

Keyphrases

• Antiproliferative Activity 100%
• Rational Design 100%
• Isatin 100%
• Molecular Docking 100%
• Rational Synthesis 100%
• Hybrid Integration 100%
• Triazole 50%
• Cytotoxicity 50%
• Strong Interaction 50%
• 5-fluorouracil (5-FU) 50%
• Cancer Cell Lines 50%
• Ovarian Cancer Cells 50%
• Cancer Cell Growth 50%
• Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) 50%
• Caspase-dependent Apoptosis 50%
• Chalcone 50%
• Azide-alkyne Cycloaddition 50%
• Docking Score 50%

Chemistry

• 1H-1,2,3-triazole 100%