Abstract
The reaction of 1-methylpyrrole with 1,3-dichloro-5,5-dimethylhydantoin gave 3-(1-methyl-1H-pyrrol-2-yl)-5,5-dimethylhydantoin and 1,3-di-(1-methyl-1H-pyrrol-2-yl)-5,5-dimethylhydantoin as products. In contrast reaction with 1,3-dichloro-5-methyl-5-phenylhydantoin (3) or 1,3-dichloro-5,5-diphenylhydantoin (4) gave only the monopyrroylhydantoin derivatives. This difference was attributed to a steric interaction between the substituents on C-5 and N1.
Original language | English (US) |
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Pages (from-to) | 1059-1064 |
Number of pages | 6 |
Journal | Heterocycles |
Volume | 36 |
Issue number | 5 |
DOIs | |
State | Published - May 1 1993 |
All Science Journal Classification (ASJC) codes
- Analytical Chemistry
- Pharmacology
- Organic Chemistry