Reaction of Bovine Conglutinin in Human in Vitro Phagocytic Systems

Göran Kronvall; John H. Dossett; Paul G. Quie; Ralph C. Williams

doi:10.3181/00379727-133-34573

Reaction of Bovine Conglutinin in Human in Vitro Phagocytic Systems

Göran Kronvall, John H. Dossett, Paul G. Quie, Ralph C. Williams

Department of Pediatrics

Research output: Contribution to journal › Article › peer-review

Abstract

Bovine conglutinin, a naturally occurring anti-C'3 factor, was studied in quantitative human in vitro phagocytosis systems. Striking antiopsonic effect was noted when conglutinin was added to phagocytic systems with gram-negative and gram-positive organisms dependent on heat-labile opsonic factors. In noncomplement-dependent test systems using isolated hyperimmune _γG opsonins, no blocking by conglutinin was noted.

Original language	English (US)
Pages (from-to)	826-830
Number of pages	5
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	133
Issue number	3
DOIs	https://doi.org/10.3181/00379727-133-34573
State	Published - Mar 1970

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology

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10.3181/00379727-133-34573

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title = "Reaction of Bovine Conglutinin in Human in Vitro Phagocytic Systems",

abstract = "Bovine conglutinin, a naturally occurring anti-C'3 factor, was studied in quantitative human in vitro phagocytosis systems. Striking antiopsonic effect was noted when conglutinin was added to phagocytic systems with gram-negative and gram-positive organisms dependent on heat-labile opsonic factors. In noncomplement-dependent test systems using isolated hyperimmune γG opsonins, no blocking by conglutinin was noted.",

author = "G{\"o}ran Kronvall and Dossett, \{John H.\} and Quie, \{Paul G.\} and Williams, \{Ralph C.\}",

note = "Funding Information: Supported in part by Grants Nos. AM 5461-05 and AI 08821-01 from the U.S. Public Health Service and in part by a grant from the Minnesota Arthritis Foundation.",

year = "1970",

month = mar,

doi = "10.3181/00379727-133-34573",

language = "English (US)",

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pages = "826--830",

journal = "Proceedings of the Society for Experimental Biology and Medicine",

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T1 - Reaction of Bovine Conglutinin in Human in Vitro Phagocytic Systems

AU - Kronvall, Göran

AU - Dossett, John H.

AU - Quie, Paul G.

AU - Williams, Ralph C.

N1 - Funding Information: Supported in part by Grants Nos. AM 5461-05 and AI 08821-01 from the U.S. Public Health Service and in part by a grant from the Minnesota Arthritis Foundation.

PY - 1970/3

Y1 - 1970/3

N2 - Bovine conglutinin, a naturally occurring anti-C'3 factor, was studied in quantitative human in vitro phagocytosis systems. Striking antiopsonic effect was noted when conglutinin was added to phagocytic systems with gram-negative and gram-positive organisms dependent on heat-labile opsonic factors. In noncomplement-dependent test systems using isolated hyperimmune γG opsonins, no blocking by conglutinin was noted.

AB - Bovine conglutinin, a naturally occurring anti-C'3 factor, was studied in quantitative human in vitro phagocytosis systems. Striking antiopsonic effect was noted when conglutinin was added to phagocytic systems with gram-negative and gram-positive organisms dependent on heat-labile opsonic factors. In noncomplement-dependent test systems using isolated hyperimmune γG opsonins, no blocking by conglutinin was noted.

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JO - Proceedings of the Society for Experimental Biology and Medicine

JF - Proceedings of the Society for Experimental Biology and Medicine

IS - 3

ER -

Reaction of Bovine Conglutinin in Human in Vitro Phagocytic Systems

Abstract

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