Reactor production of 64Cu and 67Cu using enriched zinc target material

Amanda M. Johnsen, Brenden J. Heidrich, Chad B. Durrant, Andrew J. Bascom, Kenan Ünlü

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Initial development work and trial irradiations were conducted to produce the in-demand medical isotopes 64Cu and 67Cu via the reactor-based fast neutron 64Zn(n,p)64Cu and 67Zn(n,p)67Cu reactions using enriched zinc targets. Boron-nitride shielded sample holders were used to reduce the thermal neutron flux to the zinc targets and diminish the production of undesired 65Zn. Irradiated oxide targets were dissolved and preliminary separations achieved copper yields of ~95 % and zinc separations factors greater than 103 after one ion exchange pass. Further development would allow the production of mCi levels of 64Cu and 67Cu per irradiation, providing sufficient activity for small mammal research studies.

Original languageEnglish (US)
Pages (from-to)61-71
Number of pages11
JournalJournal of Radioanalytical and Nuclear Chemistry
Issue number1
StatePublished - Jul 8 2015

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Nuclear Energy and Engineering
  • Radiology Nuclear Medicine and imaging
  • Pollution
  • Spectroscopy
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis


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