Recent advances in capillary electrophoretic analysis of individual cells

Imee G. Arcibal, Michael F. Santillo, Andrew G. Ewing

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

Because variability exists within populations of cells, single-cell analysis has become increasingly important for probing complex cellular environments. Capillary electrophoresis (CE) is an excellent technique for identifying and quantifying the contents of single cells owing to its small volume requirements and fast, efficient separations with highly sensitive detection. Recent progress in both whole-cell and subcellular sampling has allowed researchers to study cellular function in the areas of neuroscience, oncology, enzymology, immunology, and gene expression.

Original languageEnglish (US)
Pages (from-to)51-57
Number of pages7
JournalAnalytical and Bioanalytical Chemistry
Volume387
Issue number1
DOIs
StatePublished - Jan 2007

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry

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