Recreating oscillatory behavior in artificial nerve cells

Seth Wolpert, Alifya E. Chinwalla

Research output: Chapter in Book/Report/Conference proceedingConference contribution


In this study, the phenomenon of cyclic inhibition between two artificial nerve cells has been recreated. Implemented by means of postinhibitory rebound, it was achieved in a mutually inhibiting pair of identical nerve cell circuits, or Neuromimes. Each Neuromime is nominally self-excitatory, with a single inhibitory input, derived from the output of its counterpart. Postinhibitory rebound is accomplished by dynamically varying the synaptic weight of that inhibitory input. The Neuromime employed is a comprehensive VLSI-based circuit with a host of features attributable to biological nerve cells. It was fabricated in two-micron CMOS technology with a total chip area of 0.6 square millimeters, and requires only a few passive discrete components for support and adjustment. The circuit was designed as a prelude to the VLSI implementation of a biologically-based neuronal oscillator.

Original languageEnglish (US)
Title of host publication1993 IEEE 19th Annual Northeasrt Bioengineering Conference
PublisherPubl by IEEE
Number of pages3
ISBN (Print)0780309251
StatePublished - 1993
EventProceedings of the 1993 IEEE 19th Annual Northeast Bioengineering Conference - Newark, NJ, USA
Duration: Mar 18 1993Mar 19 1993


OtherProceedings of the 1993 IEEE 19th Annual Northeast Bioengineering Conference
CityNewark, NJ, USA

All Science Journal Classification (ASJC) codes

  • General Chemical Engineering


Dive into the research topics of 'Recreating oscillatory behavior in artificial nerve cells'. Together they form a unique fingerprint.

Cite this