TY - JOUR
T1 - Reduced energy intake and weight loss on a legume-enriched diet lead to improvements in biomarkers related to chronic disease
AU - Hartman, Terryl J.
AU - Zhang, Zhiying
AU - Albert, Paul S.
AU - Bagshaw, Deborah
AU - Mentor-Marcel, Roycelynn
AU - Mitchell, Diane C.
AU - Colburn, Nancy H.
AU - Kris-Etherton, Penny M.
AU - Lanza, Elaine
PY - 2011/7
Y1 - 2011/7
N2 - The Legume Inflammation Feeding Experiment was a randomized crossover feeding trial of a legume-enriched (250 g/d) diet among men (n = 64) characterized for colorectal adenoma and insulin resistance status. A subset of participants (n = 44) completed a third, optional 4-week period, which encouraged weight loss. Participants significantly decreased energy intake (-770.3 kcal/d) and energy density (-0.45). We observed a 4.4% decrease in weight (-4.0 + 0.4 kg), accompanied by reductions in fasting plasma glucose (-5.7%), insulin (-15.8%), serum C-peptide (-17.4%), C-reactive protein (-32.7%), soluble tumor necrosis factor α receptor I (-42%), total (-13.3%), and low-density lipoprotein cholesterol (-15.6 %). A legume-enriched low energy density diet may promote weight loss.
AB - The Legume Inflammation Feeding Experiment was a randomized crossover feeding trial of a legume-enriched (250 g/d) diet among men (n = 64) characterized for colorectal adenoma and insulin resistance status. A subset of participants (n = 44) completed a third, optional 4-week period, which encouraged weight loss. Participants significantly decreased energy intake (-770.3 kcal/d) and energy density (-0.45). We observed a 4.4% decrease in weight (-4.0 + 0.4 kg), accompanied by reductions in fasting plasma glucose (-5.7%), insulin (-15.8%), serum C-peptide (-17.4%), C-reactive protein (-32.7%), soluble tumor necrosis factor α receptor I (-42%), total (-13.3%), and low-density lipoprotein cholesterol (-15.6 %). A legume-enriched low energy density diet may promote weight loss.
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U2 - 10.1097/TIN.0b013e3182260eb3
DO - 10.1097/TIN.0b013e3182260eb3
M3 - Article
AN - SCOPUS:80051725108
SN - 0883-5691
VL - 26
SP - 208
EP - 215
JO - Topics in Clinical Nutrition
JF - Topics in Clinical Nutrition
IS - 3
ER -