Reducing susceptibility artifacts in fMRI using volume-selective z-shim compensation

Yiping P. Du, Manish Dalwani, Korey Wylie, Eric Claus, Jason R. Tregellas

Research output: Contribution to journalArticlepeer-review

58 Scopus citations


Susceptibility-induced magnetic field gradients (SFGs) can result in severe signal loss in the orbitofrontal cortex (OFC) in gradient-echo-based functional MRI (fMRI) studies. Although conventional z-shim techniques can effectively recover the MRI signal in this region, the substantial penalty in imaging time hampers their use in routine fMRI studies. A modified z-shim technique with high imaging efficiency is presented in this study. In this technique, z-shim compensations are applied only to a selective volume where the susceptibility artifact is severe. The results of an fMRI study (N = 6) demonstrate the feasibility of detecting the OFC activation with z-shim in whole-brain fMRI studies at a temporal resolution of 2 s.

Original languageEnglish (US)
Pages (from-to)396-404
Number of pages9
JournalMagnetic Resonance in Medicine
Issue number2
StatePublished - Feb 2007

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Reducing susceptibility artifacts in fMRI using volume-selective z-shim compensation'. Together they form a unique fingerprint.

Cite this