Regulation of cell cycle synchronization by decapentaplegic during Drosophila eye development

Andrea Penton; Scott B. Selleck; F. Michael Hoffmann

doi:10.1126/science.275.5297.203

Regulation of cell cycle synchronization by decapentaplegic during Drosophila eye development

Andrea Penton
, Scott B. Selleck
, F. Michael Hoffmann

Research output: Contribution to journal › Article › peer-review

76 Scopus citations

Abstract

In the developing Drosophila eye, differentiation is coordinated with synchronized progression through the cell cycle. Signaling mediated by the transforming growth factor-β-related gene decapentaplegic (dpp) was required for the synchronization of the cell cycle but not for cell fate specification. DPP may affect cell cycle synchronization by promoting cell cycle progression through the G₂-M phases. This synchronization is critical for the precise assembly of the eye.

Original language	English (US)
Pages (from-to)	203-206
Number of pages	4
Journal	Science
Volume	275
Issue number	5297
DOIs	https://doi.org/10.1126/science.275.5297.203
State	Published - Jan 10 1997

All Science Journal Classification (ASJC) codes

General

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10.1126/science.275.5297.203

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title = "Regulation of cell cycle synchronization by decapentaplegic during Drosophila eye development",

abstract = "In the developing Drosophila eye, differentiation is coordinated with synchronized progression through the cell cycle. Signaling mediated by the transforming growth factor-β-related gene decapentaplegic (dpp) was required for the synchronization of the cell cycle but not for cell fate specification. DPP may affect cell cycle synchronization by promoting cell cycle progression through the G2-M phases. This synchronization is critical for the precise assembly of the eye.",

author = "Andrea Penton and Selleck, \{Scott B.\} and Hoffmann, \{F. Michael\}",

year = "1997",

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doi = "10.1126/science.275.5297.203",

language = "English (US)",

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journal = "Science",

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T1 - Regulation of cell cycle synchronization by decapentaplegic during Drosophila eye development

AU - Penton, Andrea

AU - Selleck, Scott B.

AU - Hoffmann, F. Michael

PY - 1997/1/10

Y1 - 1997/1/10

N2 - In the developing Drosophila eye, differentiation is coordinated with synchronized progression through the cell cycle. Signaling mediated by the transforming growth factor-β-related gene decapentaplegic (dpp) was required for the synchronization of the cell cycle but not for cell fate specification. DPP may affect cell cycle synchronization by promoting cell cycle progression through the G2-M phases. This synchronization is critical for the precise assembly of the eye.

AB - In the developing Drosophila eye, differentiation is coordinated with synchronized progression through the cell cycle. Signaling mediated by the transforming growth factor-β-related gene decapentaplegic (dpp) was required for the synchronization of the cell cycle but not for cell fate specification. DPP may affect cell cycle synchronization by promoting cell cycle progression through the G2-M phases. This synchronization is critical for the precise assembly of the eye.

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UR - https://www.scopus.com/pages/publications/0031022423#tab=citedBy

U2 - 10.1126/science.275.5297.203

DO - 10.1126/science.275.5297.203

M3 - Article

C2 - 8985012

AN - SCOPUS:0031022423

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VL - 275

SP - 203

EP - 206

JO - Science

JF - Science

IS - 5297

ER -

Regulation of cell cycle synchronization by decapentaplegic during Drosophila eye development

Abstract

All Science Journal Classification (ASJC) codes

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