Regulation of MMP-1 expression in response to hypoxia is dependent on the intracellular redox status of metastatic bladder cancer cells

Keyphrases

• Intracellular Redox State 100%
• Hypoxia 100%
• Hypoxia Response 100%
• Matrix metalloproteinase-1 (MMP-1) 100%
• Metastatic Bladder Cancer 100%
• Bladder Cancer Cells 100%
• Hypoxia-inducible Transcription Factor 50%
• Reactive Oxygen Species 37%
• Intracellular Reactive Oxygen Species 37%
• Steady State 25%
• Cell Culture 12%
• Metastasis 12%
• Disease Progression 12%
• New Evidence 12%
• Tumor Cells 12%
• Malignancy 12%
• RNA Interference 12%
• Metastatic Disease 12%
• Antioxidant 12%
• Signaling Events 12%
• Cell Surface Display 12%
• Hypoxic Response 12%
• Interference Test 12%
• Pro-metastatic 12%
• Metastatic Progression 12%
• Redox Environment 12%
• Intracellular H2O2 12%
• N-acetylcysteine 12%
• Progression Model 12%
• Matrix metalloproteinase-2 (MMP-2) 12%
• Reactive Oxygen Species Generation 12%
• Hypoxic Conditions 12%

Immunology and Microbiology

• Cancer Cell 100%
• Dioxygen 100%
• Tumor Cell 42%
• Steady State 28%
• Transcription Factors 28%
• Cell Culture 14%
• Hydrogen Peroxide 14%
• Tumor Spheroid 14%
• Fibrinogen 14%
• Cysteine 14%
• RNAI 14%
• Acetic Acid Derivative 14%

Biochemistry, Genetics and Molecular Biology

• Cancer Cell 100%
• Interstitial Collagenase 100%
• Steady State 25%
• Transcription Factors 25%
• Transcription Factor II 25%
• Cell Culture 12%
• Hydrogen Peroxide 12%
• Tumor Spheroid 12%
• Matrix Metalloproteinase 12%
• Cysteine 12%
• Fibrinogen 12%
• RNAI 12%