TY - JOUR
T1 - Removal of myomas in asymptomatic patients to improve fertility and/or reduce miscarriage rate
T2 - a guideline
AU - Practice Committee of the American Society for Reproductive Medicine
AU - Penzias, Alan
AU - Bendikson, Kristin
AU - Butts, Samantha
AU - Coutifaris, Christos
AU - Falcone, Tommaso
AU - Fossum, Gregory
AU - Gracia, Clarisa
AU - Hansen, Karl
AU - La Barbera, Andrew
AU - Mersereau, Jennifer
AU - Odem, Randall
AU - Paulson, Richard
AU - Pfeifer, Samantha
AU - Pisarska, Margareta
AU - Rebar, Robert
AU - Reindollar, Richard
AU - Rosen, Mitchell
AU - Sandlow, Jay
AU - Vernon, Michael
N1 - Publisher Copyright:
© 2017
PY - 2017/9
Y1 - 2017/9
N2 - The purpose of this systematic review is to evaluate if uterine myomas impact the likelihood of pregnancy and pregnancy loss, and if myomectomy influences pregnancy outcomes in asymptomatic women. There is insufficient evidence to conclude that the presence of myomas reduces the likelihood of achieving pregnancy. However, there is fair evidence that myomectomy (open or laparoscopic) for cavity-distorting myomas (intramural or intramural with a submucosal component) improves pregnancy rates and reduces the risk of early pregnancy loss. There is fair evidence that hysteroscopic myomectomy for cavity-distorting myomas improves clinical pregnancy rates but insufficient evidence regarding the impact of this procedure on the likelihood of live birth or early pregnancy loss. In women with asymptomatic cavity-distorting myomas, myomectomy may be considered to optimize pregnancy outcomes.
AB - The purpose of this systematic review is to evaluate if uterine myomas impact the likelihood of pregnancy and pregnancy loss, and if myomectomy influences pregnancy outcomes in asymptomatic women. There is insufficient evidence to conclude that the presence of myomas reduces the likelihood of achieving pregnancy. However, there is fair evidence that myomectomy (open or laparoscopic) for cavity-distorting myomas (intramural or intramural with a submucosal component) improves pregnancy rates and reduces the risk of early pregnancy loss. There is fair evidence that hysteroscopic myomectomy for cavity-distorting myomas improves clinical pregnancy rates but insufficient evidence regarding the impact of this procedure on the likelihood of live birth or early pregnancy loss. In women with asymptomatic cavity-distorting myomas, myomectomy may be considered to optimize pregnancy outcomes.
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U2 - 10.1016/j.fertnstert.2017.06.034
DO - 10.1016/j.fertnstert.2017.06.034
M3 - Article
C2 - 28865538
AN - SCOPUS:85028695273
SN - 0015-0282
VL - 108
SP - 416
EP - 425
JO - Fertility and sterility
JF - Fertility and sterility
IS - 3
ER -