TY - JOUR
T1 - Rerandomization to Balance Tiers of Covariates
AU - Morgan, Kari Lock
AU - Rubin, Donald B.
N1 - Funding Information:
Kari Lock Morgan is Assistant Professor, Department of Statistics, Penn State University, University Park, PA 16802 (E-mail: [email protected]). Donald B. Rubin is John L. Loeb Professor, Department of Statistics, Harvard University, Cambridge, MA 02138 (E-mail: [email protected]). This work was partially supported by the National Science Foundation (NSF SES-0550887 and NSF IIS-1017967) and the National Institutes of Health (NIH-R01DA023879). The authors are grateful for helpful comments from Peng Ding.
Publisher Copyright:
© 2015, © American Statistical Association.
PY - 2015/10/2
Y1 - 2015/10/2
N2 - When conducting a randomized experiment, if an allocation yields treatment groups that differ meaningfully with respect to relevant covariates, groups should be rerandomized. The process involves specifying an explicit criterion for whether an allocation is acceptable, based on a measure of covariate balance, and rerandomizing units until an acceptable allocation is obtained. Here, we illustrate how rerandomization could have improved the design of an already conducted randomized experiment on vocabulary and mathematics training programs, then provide a rerandomization procedure for covariates that vary in importance, and finally offer other extensions for rerandomization, including methods addressing computational efficiency. When covariates vary in a priori importance, better balance should be required for more important covariates. Rerandomization based on Mahalanobis distance preserves the joint distribution of covariates, but balances all covariates equally. Here, we propose rerandomizing based on Mahalanobis distance within tiers of covariate importance. Because balancing covariates in one tier will in general also partially balance covariates in other tiers, for each subsequent tier we explicitly balance only the components orthogonal to covariates in more important tiers.
AB - When conducting a randomized experiment, if an allocation yields treatment groups that differ meaningfully with respect to relevant covariates, groups should be rerandomized. The process involves specifying an explicit criterion for whether an allocation is acceptable, based on a measure of covariate balance, and rerandomizing units until an acceptable allocation is obtained. Here, we illustrate how rerandomization could have improved the design of an already conducted randomized experiment on vocabulary and mathematics training programs, then provide a rerandomization procedure for covariates that vary in importance, and finally offer other extensions for rerandomization, including methods addressing computational efficiency. When covariates vary in a priori importance, better balance should be required for more important covariates. Rerandomization based on Mahalanobis distance preserves the joint distribution of covariates, but balances all covariates equally. Here, we propose rerandomizing based on Mahalanobis distance within tiers of covariate importance. Because balancing covariates in one tier will in general also partially balance covariates in other tiers, for each subsequent tier we explicitly balance only the components orthogonal to covariates in more important tiers.
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U2 - 10.1080/01621459.2015.1079528
DO - 10.1080/01621459.2015.1079528
M3 - Article
C2 - 27695149
AN - SCOPUS:84954452414
SN - 0162-1459
VL - 110
SP - 1412
EP - 1421
JO - Journal of the American Statistical Association
JF - Journal of the American Statistical Association
IS - 512
ER -