Rhegmatogenous retinal detachment in retinoblastoma patients undergoing chemoreduction and cryotherapy

Scott R. Anagnoste, Ingrid U. Scott, Timothy G. Murray, Deborah Kramer, Stuart Toledano

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21 Scopus citations


PURPOSE: To report the development of rhegmatogenous retinal detachment, with the retinal break adjacent to a cryotherapy scar, in three patients undergoing systemic chemotherapy for intraocular retinoblastoma. METHOD: Case series. RESULTS: Three patients with intraocular retinoblastoma were referred after poor response to systemic chemotherapy and local cryotherapy; three eyes of these three patients were noted to have rhegmatogenous retinal detachment and active retinoblastoma, with retinal breaks adjacent to cryotherapy scars. CONCLUSION: Rhegmatogenous retinal detachment may result from retinal necrosis associated with cryotherapy in the setting of intraocular retinoblastoma treated with systemic chemotherapy and local cryotherapy. Copyright (C) 2000 Elsevier Science Inc.

Original languageEnglish (US)
Pages (from-to)817-819
Number of pages3
JournalAmerican Journal of Ophthalmology
Issue number6
StatePublished - Jun 2000

All Science Journal Classification (ASJC) codes

  • Ophthalmology


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