Ribosome collisions: New ways to initiate ribosome rescue

Stephanie L. Leedom; Kenneth C. Keiler

doi:10.1016/j.cub.2022.04.038

Ribosome collisions: New ways to initiate ribosome rescue

Stephanie L. Leedom
, Kenneth C. Keiler

Research output: Contribution to journal › Comment/debate › peer-review

2 Scopus citations

Abstract

When ribosomes collide while translating the same mRNA, a MutS-like protein can pry apart the leading ribosome and a nuclease can cut the mRNA between the collided ribosomes to initiate ribosome rescue and recycling.

Original language	English (US)
Pages (from-to)	R469-R472
Journal	Current Biology
Volume	32
Issue number	10
DOIs	https://doi.org/10.1016/j.cub.2022.04.038
State	Published - May 23 2022

All Science Journal Classification (ASJC) codes

General Neuroscience
General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences

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10.1016/j.cub.2022.04.038

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title = "Ribosome collisions: New ways to initiate ribosome rescue",

abstract = "When ribosomes collide while translating the same mRNA, a MutS-like protein can pry apart the leading ribosome and a nuclease can cut the mRNA between the collided ribosomes to initiate ribosome rescue and recycling.",

author = "Leedom, \{Stephanie L.\} and Keiler, \{Kenneth C.\}",

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year = "2022",

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doi = "10.1016/j.cub.2022.04.038",

language = "English (US)",

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T1 - Ribosome collisions

T2 - New ways to initiate ribosome rescue

AU - Leedom, Stephanie L.

AU - Keiler, Kenneth C.

PY - 2022/5/23

Y1 - 2022/5/23

N2 - When ribosomes collide while translating the same mRNA, a MutS-like protein can pry apart the leading ribosome and a nuclease can cut the mRNA between the collided ribosomes to initiate ribosome rescue and recycling.

AB - When ribosomes collide while translating the same mRNA, a MutS-like protein can pry apart the leading ribosome and a nuclease can cut the mRNA between the collided ribosomes to initiate ribosome rescue and recycling.

UR - https://www.scopus.com/pages/publications/85130390750

UR - https://www.scopus.com/pages/publications/85130390750#tab=citedBy

U2 - 10.1016/j.cub.2022.04.038

DO - 10.1016/j.cub.2022.04.038

M3 - Comment/debate

C2 - 35609545

AN - SCOPUS:85130390750

SN - 0960-9822

VL - 32

SP - R469-R472

JO - Current Biology

JF - Current Biology

IS - 10

ER -

Ribosome collisions: New ways to initiate ribosome rescue

Abstract

All Science Journal Classification (ASJC) codes

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