RNA interference in insect pest management: Assessing potential benefits and environmental risk

Ana María Vélez, Blair D. Siegfried

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

RNA interference involves the downregulation of gene expression by exogenous double stranded RNA molecules (dsRNA). RNAi has facilitated significant technological advances in diverse fields from functional genomics to agricultural biotechnology and pest management. Recent studies have demonstrated that RNAi responses in insects can be achieved by exposure to dsRNA in artificial diet or expressed in transgenic host plants, resulting in mortality of targeted species. There is clear evidence for potential applications of RNAi for the control of insect pests. However, the environmental and ecological risks of RNAi including potential toxicity to non-target organisms, environmental fate and the risk of resistance evolution have yet to be determined.

Original languageEnglish (US)
Title of host publicationACS Symposium Series
PublisherAmerican Chemical Society
Pages59-70
Number of pages12
ISBN (Electronic)9780841229990
DOIs
StatePublished - 2014

Publication series

NameACS Symposium Series
Volume1172
ISSN (Print)0097-6156
ISSN (Electronic)1947-5918

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • General Chemical Engineering

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