Role of the glycocalyx in leukocyte-endothelial cell adhesion

Aaron Mulivor, Herbert Lipowsky

Research output: Contribution to journalConference articlepeer-review


The endothelial cell (EC) glycocalyx has been hypothesized to inhibit binding of leukocytes (WBCs) to the EC by preventing adhesion of receptors and ligands. To explore this possibility, fluorescent microspheres (FLM, 0.1 μm), were labeled with ICAM-1 antibody 1a29 and infused into the microvasculature of rat mesentery. Adhesion of FLMs and WBCs to ECs were evaluated by intravital microscopy.

Original languageEnglish (US)
Pages (from-to)S-71
JournalAnnals of Biomedical Engineering
Issue numberSUPPL. 1
StatePublished - 2000
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: Oct 12 2000Oct 14 2000

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering


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