(S)-2-(methoxydiphenylmethyl)-1-(thiophen-3-ylmethyl)pyrrolidine

Erica Martin; A. Leigh Winfrey; Jason B. Human; C. Zachary Carlin; Daniel S. Jones; Craig A. Ogle

doi:10.1107/S1600536803026035

(S)-2-(methoxydiphenylmethyl)-1-(thiophen-3-ylmethyl)pyrrolidine

Erica Martin, A. Leigh Winfrey, Jason B. Human, C. Zachary Carlin, Daniel S. Jones, Craig A. Ogle

Ken and Mary Alice Lindquist Department of Nuclear Engineering

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The crystal and molecular structure of the title compound, C ₂₃H₂₅NOS, has been determined by means of X-ray diffraction. This compound is readily lithiated with n-butyl-lithium at the 2-position of the thiophene ring to give a chiral lithiothiophene that can be used as a chiral template for enantioselective conjugate addition of an alkyl group to an enone.

Original language	English (US)
Pages (from-to)	o1970-o1971
Journal	Acta Crystallographica Section E: Structure Reports Online
Volume	59
Issue number	12
DOIs	https://doi.org/10.1107/S1600536803026035
State	Published - Dec 2003

All Science Journal Classification (ASJC) codes

General Chemistry
General Materials Science
Condensed Matter Physics

Access to Document

10.1107/S1600536803026035

Cite this

@article{c41a86362ab8466aae7b7da64052678a,

title = "(S)-2-(methoxydiphenylmethyl)-1-(thiophen-3-ylmethyl)pyrrolidine",

abstract = "The crystal and molecular structure of the title compound, C 23H25NOS, has been determined by means of X-ray diffraction. This compound is readily lithiated with n-butyl-lithium at the 2-position of the thiophene ring to give a chiral lithiothiophene that can be used as a chiral template for enantioselective conjugate addition of an alkyl group to an enone.",

author = "Erica Martin and Winfrey, \{A. Leigh\} and Human, \{Jason B.\} and Carlin, \{C. Zachary\} and Jones, \{Daniel S.\} and Ogle, \{Craig A.\}",

year = "2003",

month = dec,

doi = "10.1107/S1600536803026035",

language = "English (US)",

volume = "59",

pages = "o1970--o1971",

journal = "Acta Crystallographica Section E: Structure Reports Online",

issn = "1600-5368",

publisher = "International Union of Crystallography",

number = "12",

}

TY - JOUR

T1 - (S)-2-(methoxydiphenylmethyl)-1-(thiophen-3-ylmethyl)pyrrolidine

AU - Martin, Erica

AU - Winfrey, A. Leigh

AU - Human, Jason B.

AU - Carlin, C. Zachary

AU - Jones, Daniel S.

AU - Ogle, Craig A.

PY - 2003/12

Y1 - 2003/12

N2 - The crystal and molecular structure of the title compound, C 23H25NOS, has been determined by means of X-ray diffraction. This compound is readily lithiated with n-butyl-lithium at the 2-position of the thiophene ring to give a chiral lithiothiophene that can be used as a chiral template for enantioselective conjugate addition of an alkyl group to an enone.

AB - The crystal and molecular structure of the title compound, C 23H25NOS, has been determined by means of X-ray diffraction. This compound is readily lithiated with n-butyl-lithium at the 2-position of the thiophene ring to give a chiral lithiothiophene that can be used as a chiral template for enantioselective conjugate addition of an alkyl group to an enone.

UR - https://www.scopus.com/pages/publications/18444408676

UR - https://www.scopus.com/inward/citedby.url?scp=18444408676&partnerID=8YFLogxK

U2 - 10.1107/S1600536803026035

DO - 10.1107/S1600536803026035

M3 - Article

AN - SCOPUS:18444408676

SN - 1600-5368

VL - 59

SP - o1970-o1971

JO - Acta Crystallographica Section E: Structure Reports Online

JF - Acta Crystallographica Section E: Structure Reports Online

IS - 12

ER -

(S)-2-(methoxydiphenylmethyl)-1-(thiophen-3-ylmethyl)pyrrolidine

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this