TY - JOUR
T1 - Sacrocolpopexy using autologous rectus fascia
T2 - Cohort study of long-term outcomes and complications
AU - Wang, Rui
AU - Reagan, Krista
AU - Boyd, Sarah
AU - Tulikangas, Paul
N1 - Funding Information:
This study was funded through internal division research funds.
Publisher Copyright:
© 2022 John Wiley & Sons Ltd.
PY - 2022/8
Y1 - 2022/8
N2 - Objective: To evaluate objective and subjective outcomes of patients who underwent sacrocolpopexy using autologous rectus fascia to provide more data regarding non-mesh alternatives in pelvic organ prolapse surgery. Design: Ambispective cohort study with retrospective and prospective data. Setting: A single academic medical centre. Population: Women who underwent abdominal sacrocolpopexy using autologous rectus fascia between January 2010 and December 2019. Methods: Patients were recruited for a follow-up visit, including completing the Pelvic Floor Distress Inventory (PFDI-20) and Pelvic Organ Prolapse Quantification (POP-Q) examination. Demographic and clinical characteristics were collected. Main outcome measures: Composite failure, anatomic failure, symptomatic failure and retreatment. Results: During the study period, 132 women underwent sacrocolpopexy using autologous rectus fascia. The median follow-up time was 2.2 years. Survival analysis showed that composite failure was 0.8% (95% CI 0.1%–5.9%) at 12 months, 3.5% (95% CI 1.1%–10.7%) at 2 years, 13.2% (95% CI 7.0%–24.3%) at 3 years and 28.3% (95% CI 17.0%–44.8%) at 5 years. The anatomic failure rate was 0% at 12 months, 1.4% (95% CI 0.2%–9.2%) at 2 years, 3.1% (95% CI 0.8%–12.0%) at 3 years and 6.8% (95% CI 2.0%–22.0%) at 5 years. The symptomatic failure rate was 0% at 12 months, 1.3% (95% CI 0.2%–9.0%) at 2 years, 2.9% (95% CI 0.7%–11.3%) at 3 years and 13.1% (95% CI 5.3%–30.3%) at 5 years. The retreatment rate was 0.8% (95% CI 0.1%–5.9%) at 12 months and 2 years, 9.4% (95% CI 4.2%–20.3%) at 3 years and 13.0% (95% CI 6.0%–27.2%) at 5 years. Conclusion: Autologous rectus fascia sacrocolpopexy may be considered a safe and effective alternative for patients who wish to avoid synthetic mesh. Tweetable abstract: Sacrocolpopexy using autologous rectus fascia is a safe and effective alternative to synthetic mesh.
AB - Objective: To evaluate objective and subjective outcomes of patients who underwent sacrocolpopexy using autologous rectus fascia to provide more data regarding non-mesh alternatives in pelvic organ prolapse surgery. Design: Ambispective cohort study with retrospective and prospective data. Setting: A single academic medical centre. Population: Women who underwent abdominal sacrocolpopexy using autologous rectus fascia between January 2010 and December 2019. Methods: Patients were recruited for a follow-up visit, including completing the Pelvic Floor Distress Inventory (PFDI-20) and Pelvic Organ Prolapse Quantification (POP-Q) examination. Demographic and clinical characteristics were collected. Main outcome measures: Composite failure, anatomic failure, symptomatic failure and retreatment. Results: During the study period, 132 women underwent sacrocolpopexy using autologous rectus fascia. The median follow-up time was 2.2 years. Survival analysis showed that composite failure was 0.8% (95% CI 0.1%–5.9%) at 12 months, 3.5% (95% CI 1.1%–10.7%) at 2 years, 13.2% (95% CI 7.0%–24.3%) at 3 years and 28.3% (95% CI 17.0%–44.8%) at 5 years. The anatomic failure rate was 0% at 12 months, 1.4% (95% CI 0.2%–9.2%) at 2 years, 3.1% (95% CI 0.8%–12.0%) at 3 years and 6.8% (95% CI 2.0%–22.0%) at 5 years. The symptomatic failure rate was 0% at 12 months, 1.3% (95% CI 0.2%–9.0%) at 2 years, 2.9% (95% CI 0.7%–11.3%) at 3 years and 13.1% (95% CI 5.3%–30.3%) at 5 years. The retreatment rate was 0.8% (95% CI 0.1%–5.9%) at 12 months and 2 years, 9.4% (95% CI 4.2%–20.3%) at 3 years and 13.0% (95% CI 6.0%–27.2%) at 5 years. Conclusion: Autologous rectus fascia sacrocolpopexy may be considered a safe and effective alternative for patients who wish to avoid synthetic mesh. Tweetable abstract: Sacrocolpopexy using autologous rectus fascia is a safe and effective alternative to synthetic mesh.
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U2 - 10.1111/1471-0528.17107
DO - 10.1111/1471-0528.17107
M3 - Article
C2 - 35104383
AN - SCOPUS:85124625191
SN - 1470-0328
VL - 129
SP - 1600
EP - 1606
JO - BJOG: An International Journal of Obstetrics and Gynaecology
JF - BJOG: An International Journal of Obstetrics and Gynaecology
IS - 9
ER -