Safety Assessment of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate as Used in Cosmetics

Christina L. Burnett; Wilma F. Bergfeld; Donald V. Belsito; Ronald A. Hill; Curtis D. Klaassen; Daniel C. Liebler; James G. Marks; Ronald C. Shank; Thomas J. Slaga; Paul W. Snyder; Lillian J. Gill; Bart Heldreth

doi:10.1177/10915818221082093

Safety Assessment of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate as Used in Cosmetics

Christina L. Burnett
, Wilma F. Bergfeld
, Donald V. Belsito
, Ronald A. Hill
, Curtis D. Klaassen
, Daniel C. Liebler
, James G. Marks
, Ronald C. Shank
, Thomas J. Slaga
, Paul W. Snyder
, Lillian J. Gill
, Bart Heldreth

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate, which functions as an oxidative hair dye ingredient. The Panel reviewed relevant data provided in this safety assessment, and concluded that 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate is safe in the present practices of use and concentration in oxidative hair dye formulations.

Original language	English (US)
Pages (from-to)	69S-79S
Journal	International journal of toxicology
Volume	41
Issue number	1_suppl
DOIs	https://doi.org/10.1177/10915818221082093
State	Published - Jun 2022

All Science Journal Classification (ASJC) codes

Toxicology

Access to Document

10.1177/10915818221082093

Cite this

Burnett, C. L., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., Marks, J. G., Shank, R. C., Slaga, T. J., Snyder, P. W., Gill, L. J., & Heldreth, B. (2022). Safety Assessment of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate as Used in Cosmetics. International journal of toxicology, 41(1_suppl), 69S-79S. https://doi.org/10.1177/10915818221082093

@article{db30a929a0bd48819c620a31264088a5,

title = "Safety Assessment of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate as Used in Cosmetics",

abstract = "The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate, which functions as an oxidative hair dye ingredient. The Panel reviewed relevant data provided in this safety assessment, and concluded that 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate is safe in the present practices of use and concentration in oxidative hair dye formulations.",

author = "Burnett, \{Christina L.\} and Bergfeld, \{Wilma F.\} and Belsito, \{Donald V.\} and Hill, \{Ronald A.\} and Klaassen, \{Curtis D.\} and Liebler, \{Daniel C.\} and Marks, \{James G.\} and Shank, \{Ronald C.\} and Slaga, \{Thomas J.\} and Snyder, \{Paul W.\} and Gill, \{Lillian J.\} and Bart Heldreth",

note = "Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Re-view. The Cosmetic Ingredient Review is financially supported by the Personal Care Products Council. Publisher Copyright: {\textcopyright} The Author(s) 2022.",

year = "2022",

month = jun,

doi = "10.1177/10915818221082093",

language = "English (US)",

volume = "41",

pages = "69S--79S",

journal = "International journal of toxicology",

issn = "1091-5818",

publisher = "SAGE Publications Inc.",

number = "1\_suppl",

}

TY - JOUR

T1 - Safety Assessment of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate as Used in Cosmetics

AU - Burnett, Christina L.

AU - Bergfeld, Wilma F.

AU - Belsito, Donald V.

AU - Hill, Ronald A.

AU - Klaassen, Curtis D.

AU - Liebler, Daniel C.

AU - Marks, James G.

AU - Shank, Ronald C.

AU - Slaga, Thomas J.

AU - Snyder, Paul W.

AU - Gill, Lillian J.

AU - Heldreth, Bart

N1 - Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Re-view. The Cosmetic Ingredient Review is financially supported by the Personal Care Products Council. Publisher Copyright: © The Author(s) 2022.

PY - 2022/6

Y1 - 2022/6

N2 - The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate, which functions as an oxidative hair dye ingredient. The Panel reviewed relevant data provided in this safety assessment, and concluded that 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate is safe in the present practices of use and concentration in oxidative hair dye formulations.

AB - The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate, which functions as an oxidative hair dye ingredient. The Panel reviewed relevant data provided in this safety assessment, and concluded that 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate is safe in the present practices of use and concentration in oxidative hair dye formulations.

UR - https://www.scopus.com/pages/publications/85131220266

UR - https://www.scopus.com/pages/publications/85131220266#tab=citedBy

U2 - 10.1177/10915818221082093

DO - 10.1177/10915818221082093

M3 - Article

C2 - 35435034

AN - SCOPUS:85131220266

SN - 1091-5818

VL - 41

SP - 69S-79S

JO - International journal of toxicology

JF - International journal of toxicology

IS - 1_suppl

ER -

Safety Assessment of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate as Used in Cosmetics

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this