Safety Assessment of Alkanoyl Lactyl Lactate Salts as Used in Cosmetics

Wilbur Johnson; Wilma F. Bergfeld; Donald V. Belsito; Ronald A. Hill; Curtis D. Klaassen; Daniel C. Liebler; James G. Marks; Ronald C. Shank; Thomas J. Slaga; Paul W. Snyder; Monice Fiume; Bart Heldreth

doi:10.1177/10915818241259694

Safety Assessment of Alkanoyl Lactyl Lactate Salts as Used in Cosmetics

Wilbur Johnson, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, Monice Fiume, Bart Heldreth

Research output: Contribution to journal › Article › peer-review

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 10 alkanoyl lactyl lactate salts. These ingredients have the surfactant function in cosmetics in common. The Panel reviewed data relevant to the safety of these ingredients, and concluded that these 10 ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment when formulated to be nonirritating and nonsensitizing, which may be based on a quantitative risk assessment (QRA) or other accepted methodologies.

Original language	English (US)
Pages (from-to)	108-129
Number of pages	22
Journal	International journal of toxicology
Volume	43
Issue number	4_suppl
DOIs	https://doi.org/10.1177/10915818241259694
State	Published - Oct 2024

All Science Journal Classification (ASJC) codes

Toxicology

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10.1177/10915818241259694

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title = "Safety Assessment of Alkanoyl Lactyl Lactate Salts as Used in Cosmetics",

abstract = "The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 10 alkanoyl lactyl lactate salts. These ingredients have the surfactant function in cosmetics in common. The Panel reviewed data relevant to the safety of these ingredients, and concluded that these 10 ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment when formulated to be nonirritating and nonsensitizing, which may be based on a quantitative risk assessment (QRA) or other accepted methodologies.",

author = "Wilbur Johnson and Bergfeld, \{Wilma F.\} and Belsito, \{Donald V.\} and Hill, \{Ronald A.\} and Klaassen, \{Curtis D.\} and Liebler, \{Daniel C.\} and Marks, \{James G.\} and Shank, \{Ronald C.\} and Slaga, \{Thomas J.\} and Snyder, \{Paul W.\} and Monice Fiume and Bart Heldreth",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2024.",

year = "2024",

month = oct,

doi = "10.1177/10915818241259694",

language = "English (US)",

volume = "43",

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TY - JOUR

T1 - Safety Assessment of Alkanoyl Lactyl Lactate Salts as Used in Cosmetics

AU - Johnson, Wilbur

AU - Bergfeld, Wilma F.

AU - Belsito, Donald V.

AU - Hill, Ronald A.

AU - Klaassen, Curtis D.

AU - Liebler, Daniel C.

AU - Marks, James G.

AU - Shank, Ronald C.

AU - Slaga, Thomas J.

AU - Snyder, Paul W.

AU - Fiume, Monice

AU - Heldreth, Bart

PY - 2024/10

Y1 - 2024/10

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AB - The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 10 alkanoyl lactyl lactate salts. These ingredients have the surfactant function in cosmetics in common. The Panel reviewed data relevant to the safety of these ingredients, and concluded that these 10 ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment when formulated to be nonirritating and nonsensitizing, which may be based on a quantitative risk assessment (QRA) or other accepted methodologies.

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JF - International journal of toxicology

IS - 4_suppl

ER -

Safety Assessment of Alkanoyl Lactyl Lactate Salts as Used in Cosmetics

Abstract

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