Safety Assessment of Bis-Diglyceryl Polyacyladipate-2 and Bis-Diglyceryl Polyacyladipate-1 as Used in Cosmetics

Monice M. Fiume; Wilma F. Bergfeld; Donald V. Belsito; Ronald A. Hill; Curtis D. Klaassen; Daniel C. Liebler; James G. Marks; Ronald C. Shank; Thomas J. Slaga; Paul W. Snyder; F. Alan Andersen

doi:10.1177/1091581813504596

Safety Assessment of Bis-Diglyceryl Polyacyladipate-2 and Bis-Diglyceryl Polyacyladipate-1 as Used in Cosmetics

Monice M. Fiume
, Wilma F. Bergfeld
, Donald V. Belsito
, Ronald A. Hill
, Curtis D. Klaassen
, Daniel C. Liebler
, James G. Marks
, Ronald C. Shank
, Thomas J. Slaga
, Paul W. Snyder
, F. Alan Andersen

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The Cosmetic Ingredient Review Expert Panel assessed the safety of bis-diglyceryl polyacyladipate-2 and bis-diglyceryl polyacyladipate-1 as used in cosmetics, finding that these ingredients are safe in cosmetic formulations in the present practices of use and concentration. Both ingredients are lanolin substitutes and are reported to function in cosmetics as skin-conditioning agents—emollients. The Panel reviewed available animal and clinical data in making its determination of safety.

Original language	English (US)
Pages (from-to)	56S-64S
Journal	International Journal of Toxicology
Volume	32
DOIs	https://doi.org/10.1177/1091581813504596
State	Published - Sep 2013

All Science Journal Classification (ASJC) codes

Toxicology

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10.1177/1091581813504596

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Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., Marks, J. G., Shank, R. C., Slaga, T. J., Snyder, P. W., & Andersen, F. A. (2013). Safety Assessment of Bis-Diglyceryl Polyacyladipate-2 and Bis-Diglyceryl Polyacyladipate-1 as Used in Cosmetics. International Journal of Toxicology, 32, 56S-64S. https://doi.org/10.1177/1091581813504596

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title = "Safety Assessment of Bis-Diglyceryl Polyacyladipate-2 and Bis-Diglyceryl Polyacyladipate-1 as Used in Cosmetics",

abstract = "The Cosmetic Ingredient Review Expert Panel assessed the safety of bis-diglyceryl polyacyladipate-2 and bis-diglyceryl polyacyladipate-1 as used in cosmetics, finding that these ingredients are safe in cosmetic formulations in the present practices of use and concentration. Both ingredients are lanolin substitutes and are reported to function in cosmetics as skin-conditioning agents—emollients. The Panel reviewed available animal and clinical data in making its determination of safety.",

author = "Fiume, \{Monice M.\} and Bergfeld, \{Wilma F.\} and Belsito, \{Donald V.\} and Hill, \{Ronald A.\} and Klaassen, \{Curtis D.\} and Liebler, \{Daniel C.\} and Marks, \{James G.\} and Shank, \{Ronald C.\} and Slaga, \{Thomas J.\} and Snyder, \{Paul W.\} and Andersen, \{F. Alan\}",

note = "Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review. The Cosmetic Ingredient Review is financially supported by the Personal Care Products Council.",

year = "2013",

month = sep,

doi = "10.1177/1091581813504596",

language = "English (US)",

volume = "32",

pages = "56S--64S",

journal = "International Journal of Toxicology",

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AU - Fiume, Monice M.

AU - Bergfeld, Wilma F.

AU - Belsito, Donald V.

AU - Hill, Ronald A.

AU - Klaassen, Curtis D.

AU - Liebler, Daniel C.

AU - Marks, James G.

AU - Shank, Ronald C.

AU - Slaga, Thomas J.

AU - Snyder, Paul W.

AU - Andersen, F. Alan

N1 - Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review. The Cosmetic Ingredient Review is financially supported by the Personal Care Products Council.

PY - 2013/9

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N2 - The Cosmetic Ingredient Review Expert Panel assessed the safety of bis-diglyceryl polyacyladipate-2 and bis-diglyceryl polyacyladipate-1 as used in cosmetics, finding that these ingredients are safe in cosmetic formulations in the present practices of use and concentration. Both ingredients are lanolin substitutes and are reported to function in cosmetics as skin-conditioning agents—emollients. The Panel reviewed available animal and clinical data in making its determination of safety.

AB - The Cosmetic Ingredient Review Expert Panel assessed the safety of bis-diglyceryl polyacyladipate-2 and bis-diglyceryl polyacyladipate-1 as used in cosmetics, finding that these ingredients are safe in cosmetic formulations in the present practices of use and concentration. Both ingredients are lanolin substitutes and are reported to function in cosmetics as skin-conditioning agents—emollients. The Panel reviewed available animal and clinical data in making its determination of safety.

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ER -

Safety Assessment of Bis-Diglyceryl Polyacyladipate-2 and Bis-Diglyceryl Polyacyladipate-1 as Used in Cosmetics

Abstract

All Science Journal Classification (ASJC) codes

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