Safety Assessment of Diacetone Alcohol as Used in Cosmetics

Priya Ferguson; Wilma F. Bergfeld; Donald V. Belsito; David E. Cohen; Curtis D. Klaassen; Daniel C. Liebler; James G. Marks; Lisa A. Peterson; Ronald C. Shank; Thomas J. Slaga; Paul W. Snyder; Monice M. Fiume; Bart Heldreth

doi:10.1177/10915818251358212

Safety Assessment of Diacetone Alcohol as Used in Cosmetics

Priya Ferguson, Wilma F. Bergfeld, Donald V. Belsito, David E. Cohen, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Lisa A. Peterson, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, Monice M. Fiume, Bart Heldreth

Research output: Contribution to journal › Review article › peer-review

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Diacetone Alcohol as used in cosmetic formulations. This ingredient is reported to function as a fragrance ingredient and solvent. The Panel considered the available data and concluded that Diacetone Alcohol is safe in cosmetics in the present practices of use and concentration described in this safety assessment.

Original language	English (US)
Pages (from-to)	69S-79S
Journal	International journal of toxicology
Volume	44
Issue number	3
DOIs	https://doi.org/10.1177/10915818251358212
State	Published - Oct 1 2025

All Science Journal Classification (ASJC) codes

Toxicology

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10.1177/10915818251358212

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title = "Safety Assessment of Diacetone Alcohol as Used in Cosmetics",

abstract = "The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Diacetone Alcohol as used in cosmetic formulations. This ingredient is reported to function as a fragrance ingredient and solvent. The Panel considered the available data and concluded that Diacetone Alcohol is safe in cosmetics in the present practices of use and concentration described in this safety assessment.",

author = "Priya Ferguson and Bergfeld, \{Wilma F.\} and Belsito, \{Donald V.\} and Cohen, \{David E.\} and Klaassen, \{Curtis D.\} and Liebler, \{Daniel C.\} and Marks, \{James G.\} and Peterson, \{Lisa A.\} and Shank, \{Ronald C.\} and Slaga, \{Thomas J.\} and Snyder, \{Paul W.\} and Fiume, \{Monice M.\} and Bart Heldreth",

year = "2025",

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doi = "10.1177/10915818251358212",

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journal = "International journal of toxicology",

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TY - JOUR

T1 - Safety Assessment of Diacetone Alcohol as Used in Cosmetics

AU - Ferguson, Priya

AU - Bergfeld, Wilma F.

AU - Belsito, Donald V.

AU - Cohen, David E.

AU - Klaassen, Curtis D.

AU - Liebler, Daniel C.

AU - Marks, James G.

AU - Peterson, Lisa A.

AU - Shank, Ronald C.

AU - Slaga, Thomas J.

AU - Snyder, Paul W.

AU - Fiume, Monice M.

AU - Heldreth, Bart

PY - 2025/10/1

Y1 - 2025/10/1

N2 - The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Diacetone Alcohol as used in cosmetic formulations. This ingredient is reported to function as a fragrance ingredient and solvent. The Panel considered the available data and concluded that Diacetone Alcohol is safe in cosmetics in the present practices of use and concentration described in this safety assessment.

AB - The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Diacetone Alcohol as used in cosmetic formulations. This ingredient is reported to function as a fragrance ingredient and solvent. The Panel considered the available data and concluded that Diacetone Alcohol is safe in cosmetics in the present practices of use and concentration described in this safety assessment.

UR - https://www.scopus.com/pages/publications/105015735014

UR - https://www.scopus.com/inward/citedby.url?scp=105015735014&partnerID=8YFLogxK

U2 - 10.1177/10915818251358212

DO - 10.1177/10915818251358212

M3 - Review article

C2 - 40932361

AN - SCOPUS:105015735014

SN - 1091-5818

VL - 44

SP - 69S-79S

JO - International journal of toxicology

JF - International journal of toxicology

IS - 3

ER -

Safety Assessment of Diacetone Alcohol as Used in Cosmetics

Abstract

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