Safety Assessment of Ethers and Esters of Ascorbic Acid as Used in Cosmetics

Wilbur Johnson, Ivan J. Boyer, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, Bart Heldreth

Research output: Contribution to journalArticlepeer-review


The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 7 ethers and esters of ascorbic acid, which collectively function as antioxidants, skin-conditioning agents, skin protectants, fragrance ingredients, and skin bleaching agents in cosmetic products. The Panel reviewed relevant data relating to the safety of these ingredients, and concluded that the ethers and esters of ascorbic acid are safe in the present practices of use and concentration, as described in this safety assessment.

Original languageEnglish (US)
Pages (from-to)57S-75S
JournalInternational journal of toxicology
Issue number2_suppl
StatePublished - Aug 2022

All Science Journal Classification (ASJC) codes

  • Toxicology


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