Safety Assessment of Hydroxypropyl Bis(N -Hydroxyethyl- p -Phenylenediamine) HCl as Used in Cosmetics

Lillian C. Becker; Wilma F. Bergfeld; Donald V. Belsito; Ronald A. Hill; Curtis D. Klaassen; Daniel C. Liebler; James G. Marks; Ronald C. Shank; Thomas J. Slaga; Paul W. Snyder; F. Alan Andersen; Lillian J. Gill

doi:10.1177/1091581816659258

Safety Assessment of Hydroxypropyl Bis(N -Hydroxyethyl- p -Phenylenediamine) HCl as Used in Cosmetics

Lillian C. Becker
, Wilma F. Bergfeld
, Donald V. Belsito
, Ronald A. Hill
, Curtis D. Klaassen
, Daniel C. Liebler
, James G. Marks
, Ronald C. Shank
, Thomas J. Slaga
, Paul W. Snyder
, F. Alan Andersen
, Lillian J. Gill

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The Cosmetic Ingredient Review Expert Panel (CIR Panel) reviewed the safety of hydroxypropyl bis(N-Hydroxyethyl-p-Phenylenediamine) HCl, which functions as an oxidative hair dye ingredient. The Panel considered relevant animal and human data provided in this safety assessment and concluded that hydroxypropyl bis(N-hydroxyethyl-p-phenylenediamine) HCl is safe for use in oxidative hair dye formulations as described in this safety assessment.

Original language	English (US)
Pages (from-to)	5S-11S
Journal	International journal of toxicology
Volume	35
Issue number	2_suppl
DOIs	https://doi.org/10.1177/1091581816659258
State	Published - Nov 1 2016

All Science Journal Classification (ASJC) codes

Toxicology

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10.1177/1091581816659258

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Becker, L. C., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., Marks, J. G., Shank, R. C., Slaga, T. J., Snyder, P. W., Andersen, F. A., & Gill, L. J. (2016). Safety Assessment of Hydroxypropyl Bis(N -Hydroxyethyl- p -Phenylenediamine) HCl as Used in Cosmetics. International journal of toxicology, 35(2_suppl), 5S-11S. https://doi.org/10.1177/1091581816659258

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title = "Safety Assessment of Hydroxypropyl Bis(N -Hydroxyethyl- p -Phenylenediamine) HCl as Used in Cosmetics",

abstract = "The Cosmetic Ingredient Review Expert Panel (CIR Panel) reviewed the safety of hydroxypropyl bis(N-Hydroxyethyl-p-Phenylenediamine) HCl, which functions as an oxidative hair dye ingredient. The Panel considered relevant animal and human data provided in this safety assessment and concluded that hydroxypropyl bis(N-hydroxyethyl-p-phenylenediamine) HCl is safe for use in oxidative hair dye formulations as described in this safety assessment.",

author = "Becker, \{Lillian C.\} and Bergfeld, \{Wilma F.\} and Belsito, \{Donald V.\} and Hill, \{Ronald A.\} and Klaassen, \{Curtis D.\} and Liebler, \{Daniel C.\} and Marks, \{James G.\} and Shank, \{Ronald C.\} and Slaga, \{Thomas J.\} and Snyder, \{Paul W.\} and Andersen, \{F. Alan\} and Gill, \{Lillian J.\}",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2016.",

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doi = "10.1177/1091581816659258",

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AU - Becker, Lillian C.

AU - Bergfeld, Wilma F.

AU - Belsito, Donald V.

AU - Hill, Ronald A.

AU - Klaassen, Curtis D.

AU - Liebler, Daniel C.

AU - Marks, James G.

AU - Shank, Ronald C.

AU - Slaga, Thomas J.

AU - Snyder, Paul W.

AU - Andersen, F. Alan

AU - Gill, Lillian J.

PY - 2016/11/1

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N2 - The Cosmetic Ingredient Review Expert Panel (CIR Panel) reviewed the safety of hydroxypropyl bis(N-Hydroxyethyl-p-Phenylenediamine) HCl, which functions as an oxidative hair dye ingredient. The Panel considered relevant animal and human data provided in this safety assessment and concluded that hydroxypropyl bis(N-hydroxyethyl-p-phenylenediamine) HCl is safe for use in oxidative hair dye formulations as described in this safety assessment.

AB - The Cosmetic Ingredient Review Expert Panel (CIR Panel) reviewed the safety of hydroxypropyl bis(N-Hydroxyethyl-p-Phenylenediamine) HCl, which functions as an oxidative hair dye ingredient. The Panel considered relevant animal and human data provided in this safety assessment and concluded that hydroxypropyl bis(N-hydroxyethyl-p-phenylenediamine) HCl is safe for use in oxidative hair dye formulations as described in this safety assessment.

UR - https://www.scopus.com/pages/publications/85000948309

UR - https://www.scopus.com/pages/publications/85000948309#tab=citedBy

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AN - SCOPUS:85000948309

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SP - 5S-11S

JO - International journal of toxicology

JF - International journal of toxicology

IS - 2_suppl

ER -

Safety Assessment of Hydroxypropyl Bis(N -Hydroxyethyl- p -Phenylenediamine) HCl as Used in Cosmetics

Abstract

All Science Journal Classification (ASJC) codes

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