Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics

Priya Cherian; Wilma F. Bergfeld; Donald V. Belsito; Curtis D. Klaassen; Daniel C. Liebler; James G. Marks; Lisa A. Peterson; Ronald C. Shank; Thomas J. Slaga; Paul W. Snyder; Monice Fiume; Bart Heldreth

doi:10.1177/10915818241297097

Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics

Priya Cherian
, Wilma F. Bergfeld
, Donald V. Belsito
, Curtis D. Klaassen
, Daniel C. Liebler
, James G. Marks
, Lisa A. Peterson
, Ronald C. Shank
, Thomas J. Slaga
, Paul W. Snyder
, Monice Fiume
, Bart Heldreth

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Mannitol, Sorbitol, and Xylitol as used in cosmetics. These ingredients are reported to function as humectants, skin-conditioning agents, or flavoring agents. The Panel considered the available data and concluded that these sugar alcohol ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment.

Original language	English (US)
Pages (from-to)	22S-43S
Journal	International Journal of Toxicology
Volume	44
Issue number	1_suppl
DOIs	https://doi.org/10.1177/10915818241297097
State	Published - Feb 2025

All Science Journal Classification (ASJC) codes

Toxicology

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10.1177/10915818241297097

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title = "Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics",

abstract = "The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Mannitol, Sorbitol, and Xylitol as used in cosmetics. These ingredients are reported to function as humectants, skin-conditioning agents, or flavoring agents. The Panel considered the available data and concluded that these sugar alcohol ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment.",

author = "Priya Cherian and Bergfeld, \{Wilma F.\} and Belsito, \{Donald V.\} and Klaassen, \{Curtis D.\} and Liebler, \{Daniel C.\} and Marks, \{James G.\} and Peterson, \{Lisa A.\} and Shank, \{Ronald C.\} and Slaga, \{Thomas J.\} and Snyder, \{Paul W.\} and Monice Fiume and Bart Heldreth",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2024.",

year = "2025",

month = feb,

doi = "10.1177/10915818241297097",

language = "English (US)",

volume = "44",

pages = "22S--43S",

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TY - JOUR

T1 - Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics

AU - Cherian, Priya

AU - Bergfeld, Wilma F.

AU - Belsito, Donald V.

AU - Klaassen, Curtis D.

AU - Liebler, Daniel C.

AU - Marks, James G.

AU - Peterson, Lisa A.

AU - Shank, Ronald C.

AU - Slaga, Thomas J.

AU - Snyder, Paul W.

AU - Fiume, Monice

AU - Heldreth, Bart

PY - 2025/2

Y1 - 2025/2

N2 - The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Mannitol, Sorbitol, and Xylitol as used in cosmetics. These ingredients are reported to function as humectants, skin-conditioning agents, or flavoring agents. The Panel considered the available data and concluded that these sugar alcohol ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment.

AB - The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Mannitol, Sorbitol, and Xylitol as used in cosmetics. These ingredients are reported to function as humectants, skin-conditioning agents, or flavoring agents. The Panel considered the available data and concluded that these sugar alcohol ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment.

UR - https://www.scopus.com/pages/publications/85213406737

UR - https://www.scopus.com/pages/publications/85213406737#tab=citedBy

U2 - 10.1177/10915818241297097

DO - 10.1177/10915818241297097

M3 - Article

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AN - SCOPUS:85213406737

SN - 1091-5818

VL - 44

SP - 22S-43S

JO - International Journal of Toxicology

JF - International Journal of Toxicology

IS - 1_suppl

ER -

Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics

Abstract

All Science Journal Classification (ASJC) codes

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