Safety Assessment of Methylxanthines as Used in Cosmetics

Priya A. Cherian; Wilma F. Bergfeld; Donald V. Belsito; Ronald A. Hill; Curtis D. Klaassen; Daniel C. Liebler; James G. Marks; Ronald C. Shank; Thomas J. Slaga; Paul W. Snyder; Monice Fiume; Bart Heldreth

doi:10.1177/10915818241260282

Safety Assessment of Methylxanthines as Used in Cosmetics

Priya A. Cherian
, Wilma F. Bergfeld
, Donald V. Belsito
, Ronald A. Hill
, Curtis D. Klaassen
, Daniel C. Liebler
, James G. Marks
, Ronald C. Shank
, Thomas J. Slaga
, Paul W. Snyder
, Monice Fiume
, Bart Heldreth

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of three methylxanthines, Caffeine, Theobromine, and Theophylline, as used in cosmetics. All of these ingredients are reported to function as skin-conditioning agents in cosmetic products. The Panel reviewed the data relevant to the safety of these ingredients and concluded that Caffeine, Theobromine, and Theophylline are safe in cosmetics in the present practices of use and concentration described in this safety assessment.

Original language	English (US)
Pages (from-to)	42-77
Number of pages	36
Journal	International Journal of Toxicology
Volume	43
Issue number	4_suppl
DOIs	https://doi.org/10.1177/10915818241260282
State	Published - Oct 2024

All Science Journal Classification (ASJC) codes

Toxicology

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10.1177/10915818241260282

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title = "Safety Assessment of Methylxanthines as Used in Cosmetics",

abstract = "The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of three methylxanthines, Caffeine, Theobromine, and Theophylline, as used in cosmetics. All of these ingredients are reported to function as skin-conditioning agents in cosmetic products. The Panel reviewed the data relevant to the safety of these ingredients and concluded that Caffeine, Theobromine, and Theophylline are safe in cosmetics in the present practices of use and concentration described in this safety assessment.",

author = "Cherian, \{Priya A.\} and Bergfeld, \{Wilma F.\} and Belsito, \{Donald V.\} and Hill, \{Ronald A.\} and Klaassen, \{Curtis D.\} and Liebler, \{Daniel C.\} and Marks, \{James G.\} and Shank, \{Ronald C.\} and Slaga, \{Thomas J.\} and Snyder, \{Paul W.\} and Monice Fiume and Bart Heldreth",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2024.",

year = "2024",

month = oct,

doi = "10.1177/10915818241260282",

language = "English (US)",

volume = "43",

pages = "42--77",

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}

TY - JOUR

T1 - Safety Assessment of Methylxanthines as Used in Cosmetics

AU - Cherian, Priya A.

AU - Bergfeld, Wilma F.

AU - Belsito, Donald V.

AU - Hill, Ronald A.

AU - Klaassen, Curtis D.

AU - Liebler, Daniel C.

AU - Marks, James G.

AU - Shank, Ronald C.

AU - Slaga, Thomas J.

AU - Snyder, Paul W.

AU - Fiume, Monice

AU - Heldreth, Bart

PY - 2024/10

Y1 - 2024/10

N2 - The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of three methylxanthines, Caffeine, Theobromine, and Theophylline, as used in cosmetics. All of these ingredients are reported to function as skin-conditioning agents in cosmetic products. The Panel reviewed the data relevant to the safety of these ingredients and concluded that Caffeine, Theobromine, and Theophylline are safe in cosmetics in the present practices of use and concentration described in this safety assessment.

AB - The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of three methylxanthines, Caffeine, Theobromine, and Theophylline, as used in cosmetics. All of these ingredients are reported to function as skin-conditioning agents in cosmetic products. The Panel reviewed the data relevant to the safety of these ingredients and concluded that Caffeine, Theobromine, and Theophylline are safe in cosmetics in the present practices of use and concentration described in this safety assessment.

UR - https://www.scopus.com/pages/publications/85200514070

UR - https://www.scopus.com/pages/publications/85200514070#tab=citedBy

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DO - 10.1177/10915818241260282

M3 - Article

C2 - 39049435

AN - SCOPUS:85200514070

SN - 1091-5818

VL - 43

SP - 42

EP - 77

JO - International Journal of Toxicology

JF - International Journal of Toxicology

IS - 4_suppl

ER -

Safety Assessment of Methylxanthines as Used in Cosmetics

Abstract

All Science Journal Classification (ASJC) codes

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