Safety Assessment of Nitrocellulose and Collodion as Used in Cosmetics

Monice M. Fiume, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, F. Alan Andersen, Lillian Gill

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


The Cosmetic Ingredient Review Expert Panel (the Panel) assessed the safety of nitrocellulose and collodion as used in cosmetics, concluding that these ingredients are safe in the present practices of use and concentration in cosmetic formulations. Both ingredients are used almost exclusively in nail product formulations. The maximum concentration of use of nitrocellulose in nail polish and enamels is 22%; for collodion, the maximum reported concentration of use in nail polish and enamel is 14%. The Panel reviewed available animal and clinical data in making its determination of safety.

Original languageEnglish (US)
Pages (from-to)50S-59S
JournalInternational journal of toxicology
StatePublished - Jul 1 2016

All Science Journal Classification (ASJC) codes

  • Toxicology


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