Safety Assessment of Polyene Group as Used in Cosmetics

Christina L. Burnett; Wilma F. Bergfeld; Donald V. Belsito; Ronald A. Hill; Curtis D. Klaassen; Daniel C. Liebler; James G. Marks; Ronald C. Shank; Thomas J. Slaga; Paul W. Snyder; Lillian J. Gill; Bart Heldreth

doi:10.1177/1091581820952385

Safety Assessment of Polyene Group as Used in Cosmetics

Christina L. Burnett, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, Lillian J. Gill, Bart Heldreth

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of polyenes, which are reported to function in cosmetics primarily as film formers and viscosity increasing agents. The Panel reviewed relevant data related to these ingredients, not inggaps in the available safety data for some of the polyenes in this safety assessment. The data available for many of the ingredients are sufficient and can be extrapolated to support the safety of the entire group because of the similarities in the chemical structures, chemical properties, use concentrations, and reported functions across the group. The Panel concluded that polyenes were safe in cosmetics in the present practices of use and concentration described in this safety assessment.

Original language	English (US)
Pages (from-to)	59S-90S
Journal	International journal of toxicology
Volume	39
Issue number	2_suppl
DOIs	https://doi.org/10.1177/1091581820952385
State	Published - Sep 1 2020

All Science Journal Classification (ASJC) codes

Toxicology

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10.1177/1091581820952385

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@article{3dc21ab4c9bc4629ae995a1750475e8e,

title = "Safety Assessment of Polyene Group as Used in Cosmetics",

abstract = "The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of polyenes, which are reported to function in cosmetics primarily as film formers and viscosity increasing agents. The Panel reviewed relevant data related to these ingredients, not inggaps in the available safety data for some of the polyenes in this safety assessment. The data available for many of the ingredients are sufficient and can be extrapolated to support the safety of the entire group because of the similarities in the chemical structures, chemical properties, use concentrations, and reported functions across the group. The Panel concluded that polyenes were safe in cosmetics in the present practices of use and concentration described in this safety assessment.",

author = "Burnett, {Christina L.} and Bergfeld, {Wilma F.} and Belsito, {Donald V.} and Hill, {Ronald A.} and Klaassen, {Curtis D.} and Liebler, {Daniel C.} and Marks, {James G.} and Shank, {Ronald C.} and Slaga, {Thomas J.} and Snyder, {Paul W.} and Gill, {Lillian J.} and Bart Heldreth",

note = "Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review. The Cosmetic Ingredient Review is financially supported by the Personal Care Products Council. Publisher Copyright: {\textcopyright} The Author(s) 2020.",

year = "2020",

month = sep,

day = "1",

doi = "10.1177/1091581820952385",

language = "English (US)",

volume = "39",

pages = "59S--90S",

journal = "International journal of toxicology",

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T1 - Safety Assessment of Polyene Group as Used in Cosmetics

AU - Burnett, Christina L.

AU - Bergfeld, Wilma F.

AU - Belsito, Donald V.

AU - Hill, Ronald A.

AU - Klaassen, Curtis D.

AU - Liebler, Daniel C.

AU - Marks, James G.

AU - Shank, Ronald C.

AU - Slaga, Thomas J.

AU - Snyder, Paul W.

AU - Gill, Lillian J.

AU - Heldreth, Bart

N1 - Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review. The Cosmetic Ingredient Review is financially supported by the Personal Care Products Council. Publisher Copyright: © The Author(s) 2020.

PY - 2020/9/1

Y1 - 2020/9/1

N2 - The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of polyenes, which are reported to function in cosmetics primarily as film formers and viscosity increasing agents. The Panel reviewed relevant data related to these ingredients, not inggaps in the available safety data for some of the polyenes in this safety assessment. The data available for many of the ingredients are sufficient and can be extrapolated to support the safety of the entire group because of the similarities in the chemical structures, chemical properties, use concentrations, and reported functions across the group. The Panel concluded that polyenes were safe in cosmetics in the present practices of use and concentration described in this safety assessment.

AB - The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of polyenes, which are reported to function in cosmetics primarily as film formers and viscosity increasing agents. The Panel reviewed relevant data related to these ingredients, not inggaps in the available safety data for some of the polyenes in this safety assessment. The data available for many of the ingredients are sufficient and can be extrapolated to support the safety of the entire group because of the similarities in the chemical structures, chemical properties, use concentrations, and reported functions across the group. The Panel concluded that polyenes were safe in cosmetics in the present practices of use and concentration described in this safety assessment.

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JO - International journal of toxicology

JF - International journal of toxicology

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ER -

Safety Assessment of Polyene Group as Used in Cosmetics

Abstract

All Science Journal Classification (ASJC) codes

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